Dysfunctions of leptin, ghrelin, BDNF and endocannabinoids in eating disorders: beyond the homeostatic control of food intake

P Monteleone, M Maj - Psychoneuroendocrinology, 2013 - Elsevier
A large body of literature documents the occurrence of alterations in the physiology of both
central and peripheral modulators of appetite in acute patients with anorexia nervosa (AN) …

Neuroendocrine dysregulation of food intake in eating disorders

P Monteleone, E Castaldo, M Maj - Regulatory Peptides, 2008 - Elsevier
Anorexia nervosa (AN) and bulimia nervosa (BN) are psychiatric disorders characterized by
abnormal eating behaviors and imbalance of energy homeostasis. Changes of both central …

Leptin, ghrelin, and endocannabinoids: potential therapeutic targets in anorexia nervosa

RK Støving, A Andries, K Brixen, A Flyvbjerg… - Journal of psychiatric …, 2009 - Elsevier
Anorexia nervosa (AN) has the highest mortality rate between psychiatric disorders, and
evidence for managing it is still very limited. So far, pharmacological treatment has focused …

Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: beyond leptin and ghrelin

LA Berner, TA Brown, JM Lavender, E Lopez… - Molecular and cellular …, 2019 - Elsevier
The pathophysiology of anorexia nervosa (AN) and bulimia nervosa (BN) are still poorly
understood, but psychobiological models have proposed a key role for disturbances in the …

Neuroendocrinology and brain imaging of reward in eating disorders: A possible key to the treatment of anorexia nervosa and bulimia nervosa

AM Monteleone, G Castellini, U Volpe, V Ricca… - Progress in neuro …, 2018 - Elsevier
Anorexia nervosa and bulimia nervosa are severe eating disorders whose etiopathogenesis
is still unknown. Clinical features suggest that eating disorders may develop as reward …

The Role of “Mixed” Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite‐Regulating Neuropeptides and Peptides of the Adipose Tissue …

K Smitka, H Papezova, K Vondra, M Hill… - International journal …, 2013 - Wiley Online Library
Eating disorders such as anorexia (AN) and bulimia nervosa (BN) are characterized by
abnormal eating behavior. The essential aspect of AN is that the individual refuses to …

Central and peripheral peptides regulating eating behaviour and energy homeostasis in anorexia nervosa and bulimia nervosa: a literature review

A Tortorella, F Brambilla, M Fabrazzo… - European Eating …, 2014 - Wiley Online Library
A large body of literature suggests the occurrence of a dysregulation in both central and
peripheral modulators of appetite in patients with anorexia nervosa (AN) and bulimia …

Leptin functioning in eating disorders

P Monteleone, A DiLieto, E Castaldo, M Maj - CNS spectrums, 2004 - cambridge.org
Leptin is an adipocyte-derived hormone, which is involved predominantly in the long-term
regulation of body weight and energy balance by acting as a hunger suppressant signal to …

Reduced plasma leptin concentrations in bulimia nervosa

TD Brewerton, MD Lesem, A Kennedy… - …, 2000 - Elsevier
Leptin is a protein produced by the ob–ob gene which inhibits food intake. Plasma levels
have previously been reported to be altered in obesity and anorexia nervosa (AN) but not …

New insights in anorexia nervosa

P Gorwood, C Blanchet-Collet, N Chartrel… - Frontiers in …, 2016 - frontiersin.org
Anorexia nervosa (AN) is classically defined as a condition in which an abnormally low body
weight is associated with an intense fear of gaining weight and distorted cognitions …