Neurobiology of overeating and obesity: the role of melanocortins and beyond

R Pandit, JW de Jong, LJMJ Vanderschuren… - European journal of …, 2011 - Elsevier
The alarming increase in the incidence of obesity and obesity-associated disorders makes
the etiology of obesity a widely studied topic today. As opposed to 'homeostatic feeding' …

Plasma leptin response to acute fasting and refeeding in untreated women with bulimia nervosa

P Monteleone, F Bortolotti, M Fabrazzo… - The Journal of …, 2000 - academic.oup.com
Leptin is known to regulate body weight, energy balance, and reproduction. Therefore,
investigation of its physiology is of obvious interest in bulimia nervosa (BN), an eating …

From disordered eating to addiction: the “food drug” in bulimia nervosa

EN Umberg, RI Shader, LKG Hsu… - Journal of clinical …, 2012 - journals.lww.com
The high prevalence of substance abuse in individuals with bulimia nervosa (BN) and the
pervasive symptom substitution in many types of drug addiction suggest that a number of …

Psychopharmacological advances in eating disorders

H Himmerich, J Treasure - Expert review of clinical pharmacology, 2018 - Taylor & Francis
ABSTRACT Introduction: Anorexia nervosa (AN), bulimia nervosa (BN) and binge eating
disorder (BED) are the primary eating disorders (EDs). The only psychopharmacological …

Neuroendocrine mechanisms regulating food intake and body weight

JE McMinn, DG Baskin, MW Schwartz - Obesity Reviews, 2000 - Wiley Online Library
In the field of obesity research, two separate lines of study have emerged which explore the
mechanism by which food intake is regulated: short‐term control of food intake, and the …

The physiology and brain mechanisms of feeding

NE Rowland, A Morien, BH Li - Nutrition, 1996 - Elsevier
This article is designed as an introduction to the major theoretical models in the field of
regulation of eating behavior, and a selective review of relevant neurobiological data. We …

Ghrelin: central and peripheral implications in anorexia nervosa

M Méquinion, F Langlet, S Zgheib, S Dickson… - Frontiers in …, 2013 - frontiersin.org
Increasing clinical and therapeutic interest in the neurobiology of eating disorders reflects
their dramatic impact on health. Chronic food restriction resulting in severe weight loss is a …

Exercise, obesity and CNS control of metabolic homeostasis: a review

JK Smith - Frontiers in physiology, 2018 - frontiersin.org
This review details the manner in which the central nervous system regulates metabolic
homeostasis in normal weight and obese rodents and humans. It includes a review of the …

The interplay between leptin, glucocorticoids, and GLP1 regulates food intake and feeding behaviour

C Perez‐Leighton, B Kerr, PE Scherer… - Biological …, 2024 - Wiley Online Library
Nutritional, endocrine, and neurological signals converge in multiple brain centres to control
feeding behaviour and food intake as part of the allostatic regulation of energy balance …

Appetite disturbance and the problems of overweight

JE Blundell - Drugs, 1990 - Springer
During the past 50 years, obesity has increasingly become a problem in Western societies. If
low energy output by these individuals (ie lack of exercise) cannot be held totally …