Childhood infections and the risk of inflammatory bowel disease

JI Wurzelmann, CM Lyles, RS Sandler - Digestive diseases and sciences, 1994 - Springer
Adults with inflammatory bowel disease from North Carolina were questioned during 1986
and 1987 to assess risk due to a variety of childhood infections and treatments with …

Investigating the hygiene hypothesis as a risk factor in pediatric onset Crohn's disease: a case-control study

DK Amre, P Lambrette, L Law, A Krupoves… - Official journal of the …, 2006 - journals.lww.com
METHODS A hospital-based case-control was carried out. Newly-diagnosed cases of CD
(n= 194), less than 20 yr of age were recruited from the gastroenterology clinic of a large …

Association of paediatric inflammatory bowel disease with other immune-mediated diseases

MD Kappelman, JA Galanko, CQ Porter… - Archives of disease in …, 2011 - adc.bmj.com
Background Associations between inflammatory bowel diseases (IBDs) and other immune-
mediated diseases have been described in adult populations. Whether such associations …

Early determinants of inflammatory bowel disease: use of two national longitudinal birth cohorts

NP Thompson, SM Montgomery… - European journal of …, 2000 - journals.lww.com
Design: The 1946 National Survey of Health & Development (NSHD) and the 1958 National
Child Development Study (NCDS) are on-going, longitudinal birth cohort studies. A nested …

Childhood factors in ulcerative colitis and Crohn's disease: an international cooperative study

T Gilat, D Hacohen, P Lilos… - Scandinavian journal of …, 1987 - Taylor & Francis
This international case control study was conducted in 14 centers in 9 countries to
investigate factors in childhood which may have a bearing on the etiology or patho-genesis …

Environmental risk factors in paediatric inflammatory bowel diseases: a population based case control study

S Baron, D Turck, C Leplat, V Merle… - Gut, 2005 - gut.bmj.com
Background: Environmental exposures in early life have been implicated in the aetiology of
inflammatory bowel disease. Objective: To examine environmental risk factors prior to the …

Breast-feeding and maternal smoking in the etiology of Crohn's disease and ulcerative colitis in childhood

A Rigas, B Rigas, M Glassman, YY Yen, SJ Lan… - Annals of …, 1993 - Elsevier
Medical records concerning pediatric or adolescent patients first diagnosed with Crohn's
disease or ulcerative colitis in two New York hospitals during a 5-year period (1986 to 1990) …

Early-life exposures associated with antibiotic use and risk of subsequent Crohn's disease

H Hildebrand, P Malmborg, J Askling… - Scandinavian journal …, 2008 - Taylor & Francis
Objective. An inappropriate immune response to normal bowel flora is implicated in the
etiology of Crohn's disease. Tolerance to bowel flora develops in infancy, so factors …

Rising incidence of inflammatory bowel disease among children: a 12-year study

HM Malaty, X Fan, AR Opekun… - Journal of pediatric …, 2010 - journals.lww.com
Objective: Data suggest an increase in the incidence of pediatric inflammatory bowel
disease (IBD). We examined the trend of the incidence of IBD in children. Patients and …

A case–control study of childhood environmental risk factors for the development of inflammatory bowel disease

MA Feeney, F Murphy, AJ Clegg… - European journal of …, 2002 - journals.lww.com
A case–control study of childhood environmental risk factors... : European Journal of
Gastroenterology & Hepatology A case–control study of childhood environmental risk factors for …