Background Medical cannabinoids differ in their pharmacology and may have different
treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and …

Importance of the field: In recent times, our knowledge of cannabinoids and the
endocannabinoid system has greatly advanced. With expanding knowledge, synthetic …

Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate
symptoms, but their efficacy for specific indications is not clear. Objective To conduct a …

Cannabinoid receptors, endocannabinoids and the enzymes responsible for their
biosynthesis and degradation constitute the endocannabinoid system. In recent decades …

Background Medicinal cannabinoids, including medicinal cannabis and pharmaceutical
cannabinoids and their synthetic derivatives, such as tetrahydrocannabinol (THC) and …

Cannabinoids are a diverse class of chemical compounds that are increasingly recognized
as potential therapeutic options for a range of conditions. While many studies and reviews of …

Background Cannabinoids are used for numerous disease indications. However,
cannabinoids can also produce adverse effects; for example, they can disturb physiological …

Objectives To assess the benefits and harms of cannabinoids in participants with pain.
Design Systematic review of randomised clinical trials with meta-analysis, Trial Sequential …

Background Marijuana appears to have anti‐epileptic effects in animals. It is not currently
known if it is effective in patients with epilepsy. Some states in the United States of America …

Objective To determine the effects of medical cannabinoids on pain, spasticity, and nausea
and vomiting, and to identify adverse events. Data sources MEDLINE, the Cochrane …