Organic compounds from diesel exhaust particles elicit a proinflammatory response in human airway epithelial cells and induce cytochrome p450 1A1 expression

V Bonvallot, A Baeza-Squiban, A Baulig… - American journal of …, 2001 - atsjournals.org
Diesel exhaust particles (DEP) are known to enhance inflammatory responses in human
volunteers. In cultured human bronchial epithelial (16HBE) cells, they induce the release of …

Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells

A Baulig, M Garlatti, V Bonvallot… - … of Physiology-Lung …, 2003 - journals.physiology.org
Diesel exhaust particles (DEP) induce a proinflammatory response in human bronchial
epithelial cells (16HBE) characterized by the release of proinflammatory cytokines after …

Benzene-extracted components are important for the major activity of diesel exhaust particles: effect on interleukin-8 gene expression in human bronchial epithelial …

S Kawasaki, H Takizawa, K Takami… - American journal of …, 2001 - atsjournals.org
Epidemiologic and experimental studies suggest that diesel exhaust particles (DEPs) may
be related to increasing respiratory mortality and morbidity. We have shown that DEPs …

Diesel exhaust particles activate human bronchial epithelial cells to express inflammatory mediators in the airways: a review

H Takizawa, T Ohtoshi, S Kawasaki, S Abe… - …, 2000 - Wiley Online Library
Objective: Epidemiological as well as experimental studies suggest that particulate air
pollutants, including diesel exhaust particles (DEP), may play a role in the recent increase of …

Diesel exhaust particles induce NF-κB activation in human bronchial epithelial cells in vitro: importance in cytokine transcription

H Takizawa, T Ohtoshi, S Kawasaki… - The Journal of …, 1999 - journals.aai.org
Fine particles derived from diesel engines (diesel exhaust particles, DEP) have attracted
attention, since their density in industrial countries seems related to the increased …

Differential transcriptional regulation of IL-8 expression by human airway epithelial cells exposed to diesel exhaust particles

TL Tal, SO Simmons, R Silbajoris, L Dailey… - Toxicology and applied …, 2010 - Elsevier
Exposure to diesel exhaust particles (DEP) induces inflammatory signaling characterized by
MAP kinase-mediated activation of NFkB and AP-1 in vitro and in bronchial biopsies …

Comparison of the pro-oxidative and proinflammatory effects of organic diesel exhaust particle chemicals in bronchial epithelial cells and macrophages

N Li, M Wang, TD Oberley, JM Sempf… - The Journal of …, 2002 - journals.aai.org
Inhaled diesel exhaust particles (DEP) exert proinflammatory effects in the respiratory tract.
This effect is related to the particle content of redox cycling chemicals and is involved in the …

Diesel exhaust particles induce CYP1A1 and pro-inflammatory responses via differential pathways in human bronchial epithelial cells

AI Totlandsdal, FR Cassee, P Schwarze… - Particle and fibre …, 2010 - Springer
Background Exposure to diesel engine exhaust particles (DEPs) has been associated with
several adverse health outcomes in which inflammation seems to play a key role. DEPs …

Inflammation‐Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro

PE Schwarze, AI Totlandsdal, M Låg… - BioMed research …, 2013 - Wiley Online Library
Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in
humans. In the development of these effects inflammation is regarded as a key process …

Human airway epithelial cells in culture for studying the molecular mechanisms of the inflammatory response triggered by diesel exhaust particles

F Marano, S Boland, V Bonvallot, A Baulig… - Cell biology and …, 2002 - Springer
Epidemiological studies have shown that particulate air pollution is linked to the increase of
morbidity and mortality due to respiratory diseases. Diesel exhaust particles (DEPs), which …