Therapeutic potential of thymoquinone in glioblastoma treatment: Targeting major gliomagenesis signaling pathways

FA Chowdhury, MK Hossain… - BioMed research …, 2018 - Wiley Online Library
Glioblastoma multiforme (GBM) is one of the most devastating brain tumors with median
survival of one year and presents unique challenges to therapy because of its aggressive …

Therapeutic effects of thymoquinone for the treatment of central nervous system tumors: A review

T Farkhondeh, S Samarghandian, S Hozeifi… - Biomedicine & …, 2017 - Elsevier
Background The aim of this study is to review the effects of thymoquinone (TQ) against
central nervous systems (CNS) tumors. Methods In this study, we extensively reviewed all …

[HTML][HTML] Thymoquinone as a potential adjuvant therapy for cancer treatment: evidence from preclinical studies

AGM Mostofa, MK Hossain, D Basak… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone (TQ), the main bioactive component of Nigella sativa, has been found to
exhibit anticancer effects in numerous preclinical studies. Due to its multitargeting nature, TQ …

[HTML][HTML] Thymoquinone, as a novel therapeutic candidate of cancers

B Almajali, HAN Al-Jamal, WRW Taib, I Ismail… - Pharmaceuticals, 2021 - mdpi.com
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …

Targeting kinases with thymoquinone: A molecular approach to cancer therapeutics

SS Afrose, M Junaid, Y Akter, M Tania, M Zheng… - Drug Discovery …, 2020 - Elsevier
Highlights•Kinases are important enzymes, abnormally expressed in cancer.•Kinases are
potential targets of anticancer drugs.•Thymoquinone is a natural compound with anticancer …

Thymoquinone anticancer discovery: possible mechanisms

AH El-Far - Current drug discovery technologies, 2015 - ingentaconnect.com
Medicinal plants are known for their many advantages, including the ability to treat diseases
such as cancer. Nigella sativa and its active constituent thymoquinone (TQ) have long been …

Thymoquinone, an active compound of Nigella sativa: role in prevention and treatment of cancer

SA Almatroodi, A Almatroudi, MA Alsahli… - Current …, 2020 - ingentaconnect.com
Background: Cancer is the leading cause of death worldwide and the current mode of
cancer treatment causes side effects on normal cells and are still the key challenges in its' …

Combinatorial effect of thymoquinone with chemo agents for tumor therapy

S Jehan, J Huang, U Farooq, I Basheer, W Zhou - Phytomedicine, 2022 - Elsevier
Background Most chemotherapeutics used in cancer therapies exhibit considerable side
effects to the patients. Thus, developing new chemo agents to treat cancer patients with …

Review on molecular and therapeutic potential of thymoquinone in cancer

S Banerjee, S Padhye, A Azmi, Z Wang… - Nutrition and …, 2010 - Taylor & Francis
Thymoquinone (TQ) is the predominant bioactive constituent present in black seed oil
(Nigella sativa) and has been tested for its efficacy against cancer. Here, we summarize the …

[HTML][HTML] Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer

F Sheikhnia, V Rashidi, H Maghsoudi… - Cancer cell …, 2023 - Springer
Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide.
Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional …