Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint

M Faysal, J Khan, M Zehravi, N Nath, LP Singh… - Chinese medicine, 2023 - Springer
Honokiol is a neolignan biphenol found in aerial parts of the Magnolia plant species. The
Magnolia plant species traditionally belong to China and have been used for centuries to …

Honokiol: A review of its pharmacological potential and therapeutic insights

A Rauf, A Olatunde, M Imran, FA Alhumaydhi… - Phytomedicine, 2021 - Elsevier
Background Honokiol is a pleiotropic compound which been isolated from Magnolia species
such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia …

Neuro-modulating effects of honokiol: a review

A Woodbury, SP Yu, L Wei, P García - Frontiers in neurology, 2013 - frontiersin.org
Honokiol is a poly-phenolic compound that exerts neuroprotective properties through a
variety of mechanisms. It has therapeutic potential in anxiety, pain, cerebrovascular injury …

N europrotective effects of honokiol: from chemistry to medicine

S Talarek, J Listos, D Barreca, E Tellone, A Sureda… - Biofactors, 2017 - Wiley Online Library
The incidence of neurological disorders is growing in developed countries together with
increased lifespan. Nowadays, there are still no effective treatments for neurodegenerative …

Honokiol: A naturally occurring lignan with pleiotropic bioactivities

C Cheng, QW Zhang, YE Yang, LIN Li-Gen - Chinese journal of natural …, 2021 - Elsevier
Honokiol is the dominant biphenolic compound isolated from the Magnolia tree, and has
long been considered as the active constituent of the traditional Chinese herb,'Houpo' …

The neuropharmacological effects of magnolol and honokiol: a review of signal pathways and molecular mechanisms

X Dai, L Xie, K Liu, Y Liang, Y Cao, J Lu… - Current molecular …, 2023 - ingentaconnect.com
Magnolol and honokiol are natural lignans with good physiological effects. As the main
active substances derived from Magnolia officinalis, their pharmacological activities have …

Delivery Strategies, Structural Modification, and Pharmacological Mechanisms of Honokiol: A Comprehensive Review

C Pan, Q Li, S Xiong, Y Yang, Y Yang… - Chemistry & …, 2024 - Wiley Online Library
Honokiol (HK) is a traditional Chinese herbal bioactive compound that originates mainly
from the Magnolia species, traditionally used to treat anxiety and stroke, as well as …

Overview of the pharmacological features of honokiol

Y Maruyama, H Kuribara - CNS Drug Reviews, 2000 - Wiley Online Library
This paper provides an overview of the pharmacological features of honokiol (3′, 5‐di‐2‐
propenyl‐1, 1′‐biphenyl‐2, 4′‐diol), an isomer of neolignans isolated and identified from …

Honokiol analogs: a novel class of anticancer agents targeting cell signaling pathways and other bioactivities

A Kumar, U Kumar Singh… - Future Medicinal …, 2013 - Taylor & Francis
Honokiol (3, 5-di-(2-propenyl)-1, 1-biphenyl-2, 2-diol) is a natural bioactive neolignan
isolated from the genus Magnolia. In recent studies, honokiol has been observed to have …

Neuroprotective Potency of Neolignans in Magnolia officinalis Cortex Against Brain Disorders

S Zhu, F Liu, R Zhang, Z Xiong, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
In recent years, neurological diseases including Alzheimer's disease, Parkinson's disease
and stroke are one of the main causes of death in the world. At the same time, the incidence …