The immune system specifically recognizes and eliminates foreign antigens and thus
protects the integrity of the host. During maturation of the immune system, tolerance …

The immune system specifically recognizes and eliminates foreign antigens and, thus,
protects integrity of the host. During maturation of the immune system, tolerance …

Autoimmune reactions reflect an imbalance between effector and regulatory immune
responses, typically develop through stages of initiation and propagation, and often show …

Autoantibodies and autoreactive T cells, which exist even in healthy individuals, are usually
regulated by a mechanism called immunological tolerance. For example, peripheral T cells …

The immune system specifically recognizes and eliminates foreign agents thereby protecting
the host against infection. During maturation of the immune system, immune cells that react …

Autoimmunity is mediated by a variety of mechanisms, molecular and cellular events, and
responses. Predisposition to a given autoimmune response requires the requisite allele (s) …

There are over 80 defined autoimmune diseases, characterized by the activation of the
immune system and tissue damage in the absence of an external threat to the organism …

The 90s have been a period of explosive development of interest in, and approaches to, the
study of autoimmune disease. As we approach the end of the first half of this decade, it may …

In this two-part series, Argyrios N. Theofilopoulos summarizes the current state of affairs in
the field of autoimmunity. Part I integrates the collective mechanistic theories of autoimmune …

Autoimmunity may be initiated by a variety of mechanisms involving changes in autologous
antigens or alterations in immune regulation. Autoimmune disease, the pathological …