The dopamine D3 receptor has been implicated as a potential target for drug development
in various complex psychiatric disorders including psychosis, drug dependence, and …

Homology model structures of the dopamine D2 receptor (D2R) were generated starting
from the active and inactive states of\upbeta β 2-adrenergic crystal structure templates. To …

Abstract Structure‐based virtual screening using a D2 receptor homology model was
performed to identify dopamine D2 receptor ligands as potential antipsychotics. From …

The dopamine D3 receptor is a target of pharmacotherapeutic interest in a variety of
neurological disorders including schizophrenia, restless leg syndrome, and drug addiction …

Computer-aided conformational analysis was used to characterize the agonist
pharmacophore for D1 dopamine receptor recognition and activation. Dihydrexidine (DHX) …

In order to apply structure-based drug design techniques to G protein-coupled receptor
complexes, it is essential to model their 3D structure and to identify regions that are suitable …

Determination of quantitative structure− activity relationships (QSAR) for affinity at particular
dopamine (DA) receptors has become an even greater priority with the cloning of five DA …

The D2 dopamine receptor (DRD2) is one of the most well-established therapeutic targets
for neuropsychiatric and endocrine disorders. Most clinically approved and investigational …

The dopamine D3 receptor is recognized as a potential therapeutic target for the treatment of
various neurological and psychiatric disorders. Targetting high affinity and D3 versus D2 …

The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several
recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged …