Background: Chemokines are involved in almost all aspects of tumour establishment and
progression. Objective: This review gives an insight into the complexity of chemokines and …

Chemokines are small secreted proteins that orchestrate migration and positioning of
immune cells within the tissues. Chemokines are essential for the function of the immune …

Immunotherapeutic treatment strategies greatly extend patient survival following malignant
disease across a wide range of tumor types, including even those with metastatic disease …

The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …

Innate and adaptive immune cells can intervene during tumor progression at different stages
including initiation, angiogenesis, local spreading and distant metastasis formation. The net …

Chemokines are key molecules involved in the migration and homeostasis of immune cells.
However, also tumor cells use chemokine signals for different processes such as tumor …

Chemokines are chemotactic cytokines critical for homeostatic and inflammation-induced
trafficking of leukocytes during immune responses, hematopoesis, wound healing, and …

Chemokines are a large family of small chemotactic cytokines that coordinates immune cell
trafficking. In cancer, they have a pivotal role in the migration pattern of immune cells into the …

Chemokine gradients are central to the movement of cells in both homeostatic and
pathological processes. Most cancers express a complex array of chemokines that influence …

Chemokines are chemotactic cytokines that regulate the migration of immune cells.
Chemokines function as cues for the coordinated recruitment of immune cells into and out of …