The role of the adipocyte hormone adiponectin in cardiovascular disease

C Hug, HF Lodish - Current opinion in pharmacology, 2005 - Elsevier
Adiponectin, a novel hormone made by fat tissue, regulates energy metabolism and
endothelial activation. Serum levels of adiponectin are reduced in conditions that are …

Adiponectin and cardiovascular disease: mechanisms and new therapeutic approaches

G Siasos, D Tousoulis, C Kollia… - Current medicinal …, 2012 - ingentaconnect.com
Adiponectin is an abundant plasma protein secreted from adipocytes. Its role in energy
homeostasis is well-known, including the regulation of hydrocarbons and lipids metabolism …

Adiponectin, a unique adipocyte-derived factor beyond hormones

N Maeda, T Funahashi, Y Matsuzawa, I Shimomura - Atherosclerosis, 2020 - Elsevier
Visceral fat accumulation has a marked impact on atherosclerotic cardiovascular diseases
and metabolic syndrome clustering diabetes, dyslipidemia, and hypertension. Adiponectin …

Adiponectin: a novel adipokine linking adipocytes and vascular function

BJ Goldstein, R Scalia - The Journal of Clinical Endocrinology & …, 2004 - academic.oup.com
Cardiovascular disease accounts for an overwhelming proportion of the morbidity and
mortality suffered by patients with obesity and type 2 diabetes mellitus, and recent work has …

Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular disease

Y Matsuzawa - Atherosclerosis supplements, 2005 - Elsevier
Adiponectin is the most abundant adipose-specific protein. Its expression is reduced in
obesity, insulin resistance and type 2 diabetes, and plasma concentrations are inversely …

Adiponectin: linking the metabolic syndrome to its cardiovascular consequences

KR Rabin, Y Kamari, I Avni, E Grossman… - Expert review of …, 2005 - Taylor & Francis
Obesity and its related disorders, glucose intolerance, hypertension and hyperlipidemia,
collectively named the metabolic syndrome, result in substantial cardiovascular morbidity …

[HTML][HTML] Adiponectin and metabolic cardiovascular diseases: Therapeutic opportunities and challenges

X Lei, S Qiu, G Yang, Q Wu - Genes & Diseases, 2023 - Elsevier
Metabolic cardiovascular diseases have become a global health concern, and some of their
risk factors are linked to several metabolic disorders. They are the leading causes of death …

Adiponectin and cardiovascular disease

R Shibata, N Ouchi, T Murohara - Circulation Journal, 2009 - jstage.jst.go.jp
Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

Adiponectin in the heart and vascular system

M Ding, EM Rzucidlo, JC Davey, Y Xie, R Liu, Y Jin… - Vitamins & …, 2012 - Elsevier
Adipose tissue is not only a storage depot for energy, but also an active endocrine tissue.
Adipokines, hormones and cytokines secreted from adipocytes, relay information about …

Protective vascular and myocardial effects of adiponectin

BJ Goldstein, RG Scalia, XL Ma - Nature clinical practice Cardiovascular …, 2009 - nature.com
Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective
effects in the vasculature and myocardium. In obesity and insulin-resistant states …