[HTML][HTML] Carbon monoxide-releasing antibacterial molecules target respiration and global transcriptional regulators
KS Davidge, G Sanguinetti, CH Yee, AG Cox… - Journal of Biological …, 2009 - ASBMB
Carbon monoxide, a classical respiratory inhibitor, also exerts vasodilatory, anti-
inflammatory, and antiapoptotic effects. CO-releasing molecules have therapeutic value …
inflammatory, and antiapoptotic effects. CO-releasing molecules have therapeutic value …
The carbon monoxide‐releasing molecule, corm‐3 (ru(co)3cl(glycinate)), targets respiration and oxidases in campylobacter jejuni, generating hydrogen peroxide
H Smith, BE Mann, R Motterlini, RK Poole - IUBMB life, 2011 - Wiley Online Library
Carbon monoxide (CO) is a classical respiratory inhibitor, but CO‐releasing molecules (CO‐
RMs) have therapeutic value, increasing phagocytosis, and reducing sepsis‐induced …
RMs) have therapeutic value, increasing phagocytosis, and reducing sepsis‐induced …
Exploring the antimicrobial action of a carbon monoxide-releasing compound through whole-genome transcription profiling of Escherichia coli
LS Nobre, F Al-Shahrour, J Dopazo… - …, 2009 - microbiologyresearch.org
We recently reported that carbon monoxide (CO) has bactericidal activity. To understand its
mode of action we analysed the gene expression changes occurring when Escherichia coli …
mode of action we analysed the gene expression changes occurring when Escherichia coli …
Analysis of the Bacterial Response to Ru(CO)3Cl(Glycinate) (CORM-3) and the Inactivated Compound Identifies the Role Played by the Ruthenium Compound and …
S McLean, R Begg, HE Jesse, BE Mann… - Antioxidants & redox …, 2013 - liebertpub.com
Abstract Aims: Carbon monoxide (CO)-releasing molecules (CO-RMs) are being developed
with the ultimate goal of safely utilizing the therapeutic potential of CO clinically. One such …
with the ultimate goal of safely utilizing the therapeutic potential of CO clinically. One such …
Antibacterial effects of carbon monoxide
J Louise Wilson, HE Jesse, RK Poole… - Current …, 2012 - ingentaconnect.com
Carbon monoxide (CO) is a colourless and odourless gas that has long been considered as
a potent respiratory poison. Recent advances have demonstrated its production by haem …
a potent respiratory poison. Recent advances have demonstrated its production by haem …
[HTML][HTML] 'Carbon-monoxide-releasing molecule-2 (CORM-2)'is a misnomer: ruthenium toxicity, not CO release, accounts for its antimicrobial effects
HM Southam, MP Williamson, JA Chapman, RL Lyon… - Antioxidants, 2021 - mdpi.com
Carbon monoxide (CO)-releasing molecules (CORMs) are used to deliver CO, a biological
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
'gasotransmitter', in biological chemistry and biomedicine. CORMs kill bacteria in culture and …
Carbon monoxide gas is not inert, but global, in its consequences for bacterial gene expression, iron acquisition, and antibiotic resistance
LK Wareham, R Begg, HE Jesse… - Antioxidants & redox …, 2016 - liebertpub.com
Aims: Carbon monoxide is a respiratory poison and gaseous signaling molecule. Although
CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in …
CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in …
[HTML][HTML] A thiol-reactive Ru (II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3
HM Southam, TW Smith, RL Lyon, C Liao, CR Trevitt… - Redox biology, 2018 - Elsevier
Carbon monoxide (CO)-releasing molecules (CORMs), mostly metal carbonyl compounds,
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
are extensively used as experimental tools to deliver CO, a biological 'gasotransmitter', in …
CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on …
JL Wilson, LK Wareham, S McLean, R Begg… - Antioxidants & redox …, 2015 - liebertpub.com
Aims: Carbon monoxide-releasing molecules (CORMs) are being developed with the
ultimate goal of safely utilizing the therapeutic potential of CO clinically, including …
ultimate goal of safely utilizing the therapeutic potential of CO clinically, including …
Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules
M Desmard, R Foresti, D Morin… - Antioxidants & redox …, 2012 - liebertpub.com
Aims: Carbon monoxide (CO) delivered in a controlled manner to cells and organisms
mediates a variety of pharmacological effects to the extent that CO-releasing molecules (CO …
mediates a variety of pharmacological effects to the extent that CO-releasing molecules (CO …