In recent decades, targeted therapeutics have significantly improved therapy results in
patients with malignant tumors of different origins. However, malignant diseases …

As proteomics technologies develop, increasing number of membrane-associated proteins
specific for cancer cells are being discovered. These proteins are of great interest …

Membrane proteins, especially plasma membrane proteins, form one of the most interesting
classes of proteins among disease biomarker candidates. Because of their localization on …

The rapidly advancing elucidation of molecular targets in human cancers during the last
decade has provided an excellent basis for the development of novel therapeutics. A huge …

Cancer has become a major public health problem worldwide. Researches focus on the
new approaches for cancer treatments that involve the specific targets of the cancer disease …

Membrane proteins are involved in the prognosis of the most common forms of cancer.
Membrane proteins are the hallmark of a cancer cell. The overexpressed membrane …

Over the past 30 years, innovative laboratory research has led to an enormous expansion in
our understanding of cellular biology and genetics. Using this knowledge, we have learnt …

Metastasis is the process whereby cancer cells disseminate and establish secondary tumors
at distant sites from the primary tumor and is estimated to be responsible for≈ 90% of all …

Cancer is a genetic disease arising from somatic mutations in cells that confer a survival
advantage and invasive properties characteristic of the malignant phenotype [1]. The …

The tremendous advances achieved in the understanding of cancer biology have delivered
unprecedented progress in molecularly targeted cancer therapy in the past decade. The fast …