The discovery of adipocytokines, products of adipose tissue, has been a turning point in the
understanding of metabolic disorders. Historically considered as a passive depot of energy …

Adipose tissue, in addition to the storage of lipids function for lipids, plays active roles in
normal metabolic homeostasis and in the development of several diseases, such as type 2 …

In recent years, the independent role of adipose tissue in the pathogenesis of obesity and
related complications has been actively discussed. Adipose tissue is also a key factor in the …

Adipose tissue is an extremely active organ, and plays a fundamental role in the genesis of
comorbidities associated with obesity. Since the discovery of leptin, an important focus has …

The concept of adipose tissue as an inactive organ, which serves only for the accumulation
and storage of energy substrates and triglycerides, has finally remained in the past. Studies …

Adipose tissue is the source of soluble mediators (adipokines), secreted mainly by
adipocytes. Leptin acts on the brain and peripheral organs to regulate energy homeostasis …

In the recent years we have begun to appreciate that adipose tissue is more than just a
passive repository for excess energy. It is a highly active endocrine organ secreting a range …

Adipose tissue secretes many adipokines that regulate important physiological functions.
Growing studies have highlighted that these bioactive molecules may contribute to the …

Visceral obesity is among the known risk factors of atherosclerotic cardiovascular diseases.
As long as adipose tissue was considered only an inert store of excess energy, accumulated …

Worldwide, the prevalence of overweight and obesity and associated complications is
increasing. Cardiovascular complications are the most important factor determining survival …