For a long time, minocycline has been recognized as highly efficacious for the treatment of
acne vulgaris but with use-limiting acute vestibular adverse events (AVAEs). Based on the …

The complete safety and efficacy of a new extended-release (ER) minocycline hydrochloride
formulation were assessed in an analysis of a phase 2 dose-finding study and 2 phase 3 …

A multicenter, 12-week, randomized, double-blinded, placebo-controlled, dose-ranging
study was conducted in 233 subjects with moderate to severe facial acne vulgaris to …

Abstract Background Carbapenem-resistant Acinetobacter baumannii infections are defined
by the WHO as a critical threat. IV minocycline is approved in the United States for treatment …

The bioequivalence of two capsule formulations containing 100 mg minocycline was
assessed in 12 healthy adult male and female volunteers in a crossover, randomized, single …

Minocycline was determined in human plasma by HPLC–MS–MS using clarithromycin as an
internal standard. The method is fast (single liquid extraction and run time of< 3 min) and …

The invention relates to pharmaceutical delivery systems for the prolonged controlled
release of 7-dime thylamino-6-deoxy-6-demethyltetracycline (minocy cline) or non-toxic acid …

A sensitive and specific high-performance liquid chromatographic method was developed
and validated for the determination of minocycline in human plasma. The method uses liquid …

Resistance of Cutibacterium acnes to topical antibiotics historically used to treat acne
(topical erythromycin and clindamycin and, more recently, topical azithromycin and …

Since the introduction of minocycline HCl in the late 1960's, it has been used for disease
states that have ranged from typical community-acquired infectious diseases to others that …