Eosinophils: singularly destructive effector cells or purveyors of immunoregulation?
EA Jacobsen, AG Taranova, NA Lee, JJ Lee - Journal of Allergy and …, 2007 - Elsevier
Eosinophils are granulocytes typically associated with immune responses to a limited
number of specific insults, including helminth infection and exposure to various allergens …
number of specific insults, including helminth infection and exposure to various allergens …
Changing roles of eosinophils in health and disease
Objective To review and highlight the unappreciated roles of eosinophils suggested by
recent studies. Data Sources The literature, unpublished observations, and insights by the …
recent studies. Data Sources The literature, unpublished observations, and insights by the …
[HTML][HTML] The emerging roles of eosinophils: implications for the targeted treatment of eosinophilic-associated inflammatory conditions
C Lombardi, A Berti, M Cottini - Current research in immunology, 2022 - Elsevier
Eosinophils have multiple relevant biological functions, including the maintenance of
homeostasis, host defense against infectious agents, innate immunity activities, immune …
homeostasis, host defense against infectious agents, innate immunity activities, immune …
Eosinophils: friends or foes?
MJ Chusid - The Journal of Allergy and Clinical Immunology: In …, 2018 - Elsevier
The roles eosinophils are recognized to play in health and disease continue to evolve.
Formerly, eosinophils were believed to fill a primary role in host defense against helminths …
Formerly, eosinophils were believed to fill a primary role in host defense against helminths …
Immunoregulatory roles of eosinophils: a new look at a familiar cell
P Akuthota, HB Wang, LA Spencer… - Clinical & Experimental …, 2008 - Wiley Online Library
Eosinophils are usually considered as end‐stage degranulating effector cells of innate
immunity. However, accumulating evidence has revealed additional roles for eosinophils …
immunity. However, accumulating evidence has revealed additional roles for eosinophils …
Contributions of eosinophils to human health and disease
AD Klion, SJ Ackerman… - Annual Review of …, 2020 - annualreviews.org
The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …
immunity but at times has also been incriminated in disease pathophysiology. Research into …
Functions of tissue-resident eosinophils
PF Weller, LA Spencer - Nature Reviews Immunology, 2017 - nature.com
Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …
helminth infection and allergic disease. Their effector functions have been attributed to their …
Eosinophils: multifaceted biological properties and roles in health and disease
H Kita - Immunological reviews, 2011 - Wiley Online Library
Eosinophils are leukocytes resident in mucosal tissues. During T‐helper 2 (Th2)‐type
inflammation, eosinophils are recruited from bone marrow and blood to the sites of immune …
inflammation, eosinophils are recruited from bone marrow and blood to the sites of immune …
Eosinophils in health and disease: the LIAR hypothesis
JJ Lee, EA Jacobsen, MP McGarry… - Clinical & …, 2010 - Wiley Online Library
Discussions of eosinophils are often descriptions of end‐stage effector cells with destructive
capabilities mediated predominantly by released cytotoxic cationic granule proteins …
capabilities mediated predominantly by released cytotoxic cationic granule proteins …
Eosinophils: changing perspectives in health and disease
HF Rosenberg, KD Dyer, PS Foster - Nature Reviews Immunology, 2013 - nature.com
Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …