It is well established that opioid systems in the brain exert an important modulatory influence
on food intake. Even before the discovery of the endogenous opioid peptides or the cloning …

It is well established that opioid systems in the brain exert an important modulatory influence
on food intake. Even before the discovery of the endogenous opioid peptides or the cloning …

Over the last decades, the importance of food in the development of chronic diseases has
been examined, as well as the medical value of eating healthy. The contribution of the …

Humans eat for many reasons, including the rewarding qualities of foods. A host of
neurotransmitters have been shown to influence eating behavior and some of these appear …

Food reward can be driven by separable mechanisms of hedonic impact (food 'liking') and
incentive motivation (food 'wanting'). Brain mu-opioid systems contribute crucially to both …

Nucleus accumbens μ-opioid stimulation causes marked increases in the intake of highly
palatable foods, such as a high-fat diet. However, to date there has been little examination of …

It is well established that opioid signaling in the central nervous system constitutes a
powerful stimulus for food intake. The role of opioids in determining food preference …

Food intake, which is a highly reinforcing behavior, provides nutrients required for survival in
all animals. However, when fat and sugar consumption goes beyond the daily needs, it can …

This thesis explores how two important areas of the brain's reward system, the nucleus
accumbens and lateral hypothalamus, control food intake and glucose metabolism. The …

Endogenous opioid peptides within the nucleus accumbens are thought to mediate the
hedonic aspects of food intake, particularly foods such as fat and sugar. In view of evidence …