A decline in mitochondrial function plays a key role in the aging process and increases the
incidence of age-related disorders, including Alzheimer disease (AD). Mitochondria—the …

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the
progressive loss of cholinergic neurons, leading to the onset of severe behavioral, motor …

Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disease and has become a
major socioeconomic issue in many developed countries. Currently available therapeutic …

Significance: Alzheimer's disease (AD) is the leading cause of dementia. Thus far, 99.6% of
clinical trials, including those targeting energy metabolism, have failed to exert disease …

Abstract Purpose of Review Mitochondria are essential for facilitating energy homeostasis
under ever-changing environmental conditions. Mitochondrial dysfunction has been …

Alzheimer's Disease (AD) is one of the most common age-related neurodegenerative
diseases in the developed world. Treatment of AD is particularly challenging as the drug …

J. Neurochem.(2010) 114, 933–945. Abstract Despite the increasing knowledge of
Alzheimer's disease (AD) management with novel pharmacologic agents, most of them are …

Alzheimer's disease is the most prevalent neurodegenerative disorder and affects the lives
not only of those who are diagnosed but also of their caregivers. Despite the enormous …

Mitochondria are dynamic ATP‐generating organelle which contribute to many cellular
functions including bioenergetics processes, intracellular calcium regulation, alteration of …