Background Osteomyelitis is a severe bone infection and typically leads to progressive bone
resorption, destruction and dysfunction. Pyroptosis is a form of programmed cell death …

Inflammatory bone diseases include osteoarthritis (OA) and rheumatoid arthritis (RA), which
can cause severe bone damage in a chronic inflammation state, putting tremendous …

Pyroptosis is a controlled form of inflammatory cell death characterized by inflammasome
activation, pore formation, and cell lysis. According to different caspases, pyroptosis can be …

Abstract Background and Objective Pyroptosis has both a caspase‐1‐dependent canonical
pathway and a caspase‐4/‐5/‐11‐dependent noncanonical pathway. They play an …

Osteoarthritis (OA) is one of the most common chronic joint diseases and is gradually
becoming the main cause of disability and joint pain in the elderly worldwide. Pyroptosis is a …

The acute inflammatory stimulation occurring after a bone fracture regulates the repair and
healing of local bone injury; however, under certain conditions, pyroptosis may occur in …

Background Pyroptosis is a recently identified pathway of caspase-mediated cell death in
response to microbes, lipopolysaccharide, or chemotherapy in certain types of cells …

Cell death is ascribed as an essential biological process that is fundamental for the
development of an organism along with its survival. The procedure comprises of apoptosis …

Increasing evidence has shown that macrophage pyroptosis in different tissues participates
in chronic aseptic inflammation and is related to tissue fibrosis. Our last studies also …

Abstract Background and Objective Occlusal trauma is considered to be a contributing factor
to bone loss associated with inflammatory periodontal disease. We hypothesized that …