The Warburg effect in 2012
JP Bayley, P Devilee - Current opinion in oncology, 2012 - journals.lww.com
The Warburg effect in 2012 : Current Opinion in Oncology The Warburg effect in 2012 : Current
Opinion in Oncology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet …
Opinion in Oncology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet …
Warburg effect or reverse Warburg effect? A review of cancer metabolism
XD Xu, SX Shao, HP Jiang, YW Cao… - Oncology research and …, 2015 - karger.com
Cancer is a major threat to human health. A considerable amount of research has focused
on elucidating the nature of cancer from its pathogenesis to treatment and prevention. Tumor …
on elucidating the nature of cancer from its pathogenesis to treatment and prevention. Tumor …
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor …
M Wu, A Neilson, AL Swift, R Moran… - … of Physiology-Cell …, 2007 - journals.physiology.org
Increased conversion of glucose to lactic acid associated with decreased mitochondrial
respiration is a unique feature of tumors first described by Otto Warburg in the 1920s. Recent …
respiration is a unique feature of tumors first described by Otto Warburg in the 1920s. Recent …
Post-translational modifications and the Warburg effect
T Hitosugi, J Chen - Oncogene, 2014 - nature.com
Post-translational modification (PTM) is an important step of signal transduction that
transfers chemical groups such as phosphate, acetyl and glycosyl groups from one protein …
transfers chemical groups such as phosphate, acetyl and glycosyl groups from one protein …
Mitochondrial dysfunction in cancer cells due to aberrant mitochondrial replication
Y Shapovalov, D Hoffman, D Zuch… - Journal of Biological …, 2011 - ASBMB
Warburg effect is a hallmark of cancer manifested by continuous prevalence of glycolysis
and dysregulation of oxidative metabolism. Glycolysis provides survival advantage to cancer …
and dysregulation of oxidative metabolism. Glycolysis provides survival advantage to cancer …
Warburg effect and redox balance
RB Hamanaka, NS Chandel - Science, 2011 - science.org
In the 1920s, German biochemist Otto Warburg demonstrated that tumor cells produce
copious amounts of lactate despite the presence of ample oxygen—a phenomenon called …
copious amounts of lactate despite the presence of ample oxygen—a phenomenon called …
The Warburg metabolism fuels tumor metastasis
J Lu - Cancer and Metastasis Reviews, 2019 - Springer
The Warburg effect is prevalent in human cancer. Accordingly, most cancer cells display
highly elevated glycolysis without proportionally increasing pyruvate oxidation. The …
highly elevated glycolysis without proportionally increasing pyruvate oxidation. The …
Contemporary perspectives on the Warburg effect inhibition in cancer therapy
K Kozal, P Jóźwiak, A Krześlak - Cancer Control, 2021 - journals.sagepub.com
In the 1920s, Otto Warburg observed the phenomenon of altered glucose metabolism in
cancer cells. Although the initial hypothesis suggested that the alteration resulted from …
cancer cells. Although the initial hypothesis suggested that the alteration resulted from …
Understanding the Warburg effect: the metabolic requirements of cell proliferation
MG Vander Heiden, LC Cantley, CB Thompson - science, 2009 - science.org
In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative
phosphorylation to generate the energy needed for cellular processes, most cancer cells …
phosphorylation to generate the energy needed for cellular processes, most cancer cells …
Warburg and beyond: the power of mitochondrial metabolism to collaborate or replace fermentative glycolysis in cancer
A defining hallmark of tumor phenotypes is uncontrolled cell proliferation, while fermentative
glycolysis has long been considered as one of the major metabolic pathways that allows …
glycolysis has long been considered as one of the major metabolic pathways that allows …