A new method for identifying essential proteins by measuring co-expression and functional similarity

W Zhang, J Xu, X Li, X Zou - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Identification of essential proteins is a fundamental task for understanding cellular life. With
the increasing availability of high-throughput data, which enable the identification of …

Identification of essential proteins by using complexes and interaction network

M Li, Y Lu, Z Niu, FX Wu, Y Pan - International Symposium on …, 2014 - Springer
Essential proteins are indispensable in maintaining the cellular life. Identification of essential
proteins can provide basis for drug target design, disease treatment as well as synthetic …

Random walk based method to identify essential proteins by integrating network topology and biological characteristics

X Lei, X Yang, H Fujita - Knowledge-Based Systems, 2019 - Elsevier
Essential proteins are regarded as the fundamental components of living organisms. The
identification of essential proteins greatly contributes to the understanding of cellular …

Predicting essential proteins based on RNA-Seq, subcellular localization and GO annotation datasets

X Lei, J Zhao, H Fujita, A Zhang - Knowledge-Based Systems, 2018 - Elsevier
Essential proteins are indispensable to cellular life. Identification of essential proteins plays
a critical role in the survival and development of life process and understanding the function …

An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information

S Li, Z Zhang, X Li, Y Tan, L Wang, Z Chen - BMC bioinformatics, 2021 - Springer
Background Essential proteins have great impacts on cell survival and development, and
played important roles in disease analysis and new drug design. However, since it is …

Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and go annotation data

W Zhang, J Xu, X Zou - IEEE/ACM transactions on …, 2019 - ieeexplore.ieee.org
Essential proteins are indispensable for maintaining normal cellular functions. Identification
of essential proteins from Protein-protein interaction (PPI) networks has become a hot topic …

A cross-entropy-based method for essential protein identification in yeast protein-protein interaction network

W Sun, L Wang, J Peng, Z Zhang, T Pei… - Current …, 2021 - ingentaconnect.com
Background: Research has shown that essential proteins play important roles in the
development and survival of organisms. Because of the high costs of traditional biological …

Predicting essential proteins based on second-order neighborhood information and information entropy

J Zhao, X Lei - IEEE Access, 2019 - ieeexplore.ieee.org
Essential proteins are critical components of living organisms and indispensable to cellular
life. Identification of essential proteins plays a critical role in the survival and development of …

A new algorithm for essential proteins identification based on the integration of protein complex co-expression information and edge clustering coefficient

J Luo, J Wu - International Journal of Data Mining and …, 2015 - inderscienceonline.com
Essential proteins provide valuable information for the development of biology and medical
research from the system level. The accuracy of topological centrality only based methods is …

An iteration method for identifying yeast essential proteins from weighted PPI network based on topological and functional features of proteins

S Li, Z Chen, X He, Z Zhang, T Pei, Y Tan… - IEEE Access, 2020 - ieeexplore.ieee.org
Accumulating studies have indicated that essential proteins play critical roles in numerous
biological processes. With the rapid development of high-throughput technologies, a large …