Emerging evidence has revealed that neutrophils have phenotypic and functional plasticity.
Neutrophils could be polarized towards a pro-tumor phenotype by tumor-derived factors. In …

Neutrophils are the predominant leucocytes in the blood and act as the first line of host
defence against invading pathogens. Neutrophils have also been shown to play important …

In gastric cancer, lymph node metastasis (LNM) is the major metastasis route, and lymphatic
invasion is the precursor of LNM. Tumor-associated neutrophils (TANs) promote LNM …

In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Neutrophils are predominant immune cells that protect the host from microbial infection. The
roles of neutrophils in tumor have long been ignored due to their short life span and terminal …

Objective Neutrophils are prominent components of solid tumours and exhibit distinct
phenotypes in different tumour microenvironments. However, the nature, regulation, function …

The role of neutrophils in cancer is still very contradictory. Several studies have
demonstrated the cytotoxic capacity of neutrophils against different types of tumors, by …

Colorectal cancer (CRC) is one of the most common causes of cancer deaths worldwide and
the number of CRC patients is increasing progressively. Despite the improvement of the …

The role neutrophils play in cancer is a matter of debate as both proand anti-tumor functions
have been documented. In a recent publication in Nature, Coffelt et al. identify a new …

Cancer is considered a major public health concern worldwide and is characterized by an
uncontrolled division of abnormal cells. The human immune system recognizes cancerous …