Hydrogen peroxide production by red blood cells

C Giulivi, P Hochstein, KJA Davies - Free Radical Biology and Medicine, 1994 - Elsevier
Red blood cells are frequently employed in studies of oxidative stress. Technical difficulties
have previously prevented the measurement of H 2 O 2 production by red blood cells …

Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes

RM Johnson, G Goyette Jr, Y Ravindranath… - Free Radical Biology and …, 2005 - Elsevier
Red cells from mice deficient in glutathione peroxidase-1 were used to estimate the
hemoglobin autoxidation rate and the endogenous level of H2O2 and superoxide …

Kinetic and stoichiometric constraints determine the pathway of H2O2 consumption by red blood cells

F Orrico, MN Möller, A Cassina, A Denicola… - Free Radical Biology …, 2018 - Elsevier
Red blood cells (RBC) are considered as a circulating sink of H 2 O 2, but a significant
debate remains over the role of the different intraerythocyte peroxidases. Herein we …

[HTML][HTML] An assay for the rate of removal of extracellular hydrogen peroxide by cells

BA Wagner, JR Witmer, TJ van't Erve, GR Buettner - Redox biology, 2013 - Elsevier
Cells have a wide range of capacities to remove extracellular hydrogen peroxide. At higher
concentrations of extracellular H 2 O 2 (micromolar) the rate of removal can be …

Erythrocyte defense against hydrogen peroxide: preeminent importance of catalase

MD Scott, BH Lubin, L Zuo… - The Journal of laboratory …, 1991 - translationalres.com
To investigate the relative importance of catalase and glutathione in erythrocyte oxidant
defense, human and mouse (normal and acatalasemic) erythrocytes were reversibly lysed …

Direct Evidence for Catalase as the Predominant H2O2 -Removing Enzyme in Human Erythrocytes

S Mueller, HD Riedel… - Blood, The Journal of the …, 1997 - ashpublications.org
Decomposition of hydrogen peroxide (H2O2) at physiological levels was studied in human
erythrocytes by means of a recently developed sensitive H2O2 assay. The exponential …

What is the concentration of hydrogen peroxide in blood and plasma?

HJ Forman, A Bernardo, KJA Davies - Archives of biochemistry and …, 2016 - Elsevier
The concentration of hydrogen peroxide (H 2 O 2) in blood and plasma is a measurement
that has often been made, but the absolute values remain unsettled due the great variability …

Importance of catalase in the disposal of hydrogen peroxide within human erythrocytes

GF Gaetani, HN Kirkman, R Mangerini, AM Ferraris - 1994 - ashpublications.org
The catalase within normal, intact human erythrocytes was completely inactivated with
amino triazole. The rate of 14CO2 evolution, when the cells were subsequently incubated …

Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical.

CC Winterbourn, A Stern - The Journal of clinical …, 1987 - Am Soc Clin Investig
The ability of intact human red cells to scavenge extracellularly generated H2O2 and O2-,
and to prevent formation of hydroxyl radicals and hypochlorous acid has been examined …

Oxygen-related processes in red blood cells exposed to tert-butyl hydroperoxide

IK Dremza, EA Lapshina, J Kujawa, IB Zavodnik - Redox Report, 2006 - Taylor & Francis
The correlation between the oxidative processes in tert-butyl hydroperoxide (tBHP)-exposed
red blood cells and the reactions of oxygen consumption and release were investigated …