Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells
SS Tseng-Rogenski, H Chung, MB Wilk, S Zhang… - PloS one, 2012 - journals.plos.org
Background Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST)
is a genetic signature observed in 60% of sporadic colorectal cancers (CRCs). Unlike …
is a genetic signature observed in 60% of sporadic colorectal cancers (CRCs). Unlike …
MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells
C Campregher, G Schmid, F Ferk, S Knasmüller… - PloS one, 2012 - journals.plos.org
Background/Aim Elevated microsatellite instability at selected tetranucleotide repeats
(EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been …
(EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been …
Relationship of EMAST and microsatellite instability among patients with rectal cancer
B Devaraj, A Lee, BL Cabrera, K Miyai, L Luo… - Journal of …, 2010 - Elsevier
Background Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is
a genetic signature identified in 60% of sporadic colon cancers and may be linked with …
a genetic signature identified in 60% of sporadic colon cancers and may be linked with …
EMAST is a form of microsatellite instability that is initiated by inflammation and modulates colorectal cancer progression
JM Carethers, M Koi, SS Tseng-Rogenski - Genes, 2015 - mdpi.com
DNA mismatch repair (MMR) function is critical for correcting errors coincident with
polymerase-driven DNA replication, and its proteins are frequent targets for inactivation …
polymerase-driven DNA replication, and its proteins are frequent targets for inactivation …
Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias
SY Lee, H Chung, B Devaraj, M Iwaizumi, HS Han… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS:: Elevated microsatellite alterations at selected tetranucleotide
repeats (EMAST) occurs during microsatellite instability (MSI) that is not associated with …
repeats (EMAST) occurs during microsatellite instability (MSI) that is not associated with …
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer
Microsatellite instability (MSI) is a hallmark of mismatch repair (MMR) deficiency. High levels
of MSI at mononucleotide and dinucleotide repeats in colorectal cancer (CRC) are attributed …
of MSI at mononucleotide and dinucleotide repeats in colorectal cancer (CRC) are attributed …
Microsatellite instability in colorectal cancer: from molecular oncogenic mechanisms to clinical implications
A Zaanan, K Meunier, F Sangar, JF Fléjou, F Praz - Cellular oncology, 2011 - Springer
Background Microsatellite instability (MSI) constitutes an important oncogenic molecular
pathway in colorectal cancer (CRC), representing approximately 15% of all colorectal …
pathway in colorectal cancer (CRC), representing approximately 15% of all colorectal …
Efficacy of adjuvant 5-fluorouracil therapy for patients with EMAST-positive stage II/III colorectal cancer
Y Hamaya, C Guarinos, SS Tseng-Rogenski… - PloS one, 2015 - journals.plos.org
Elevated Microsatellite Alterations at Selected Tetranucleotide repeats (EMAST) is a genetic
signature found in up to 60% of colorectal cancers (CRCs) that is caused by somatic …
signature found in up to 60% of colorectal cancers (CRCs) that is caused by somatic …
Immunohistochemical null-phenotype for mismatch repair proteins in colonic carcinoma associated with concurrent MLH1 hypermethylation and MSH2 somatic …
Microsatellite instability, a well-established driver pathway in colorectal carcinogenesis, can
develop in both sporadic and hereditary conditions via different molecular alterations in the …
develop in both sporadic and hereditary conditions via different molecular alterations in the …
Interleukin 6 alters localization of hMSH3, leading to DNA mismatch repair defects in colorectal cancer cells
SS Tseng-Rogenski, Y Hamaya, DY Choi… - Gastroenterology, 2015 - Elsevier
Background & Aims Elevated microsatellite alterations at selected tetranucleotide repeats
(EMAST) is the most common DNA mismatch repair defect in colorectal cancers, observed in …
(EMAST) is the most common DNA mismatch repair defect in colorectal cancers, observed in …