Prognostic significance of ferroptosis pathway gene signature and correlation with macrophage infiltration in cervical squamous cell carcinoma

CJ Li, CH Chang, YL Tsang, SH Fang, SN Chen… - International …, 2022 - Elsevier
Background Nuclear factor erythroid 2-related factor 2 (NFE2L2) plays a critical role in
ferroptosis and biogenesis, however, its role in cervical squamous cell carcinoma (CESC) …

Identification of ferroptosis-related molecular subtypes and a methylation-related ferroptosis gene prognostic signature in cervical squamous cell carcinoma

L Yu, Z Gao, Z Li, P Liu, Y Gao, G Liang - Journal of Cancer Research and …, 2023 - Springer
Purpose We aimed to investigate the molecular characteristics of cervical squamous cell
carcinoma (CESC) by analyzing ferroptosis-related gene (FRG) expression data to predict …

[HTML][HTML] Ferroptosis-related genes identify tumor immune microenvironment characterization for the prediction of prognosis in cervical cancer

X Yang, F Yin, Q Liu, Y Ma, H Zhang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Cervical cancer (CC) is a disease that affects female health; therefore, timely
prevention and diagnosis of CC are crucial to decrease its mortality. Ferroptosis, an iron …

A novel ferroptosis-related gene signature for predicting outcomes in cervical cancer

X Qi, Y Fu, J Sheng, M Zhang, M Zhang, Y Wang… - …, 2021 - Taylor & Francis
Ferroptosis, a newly discovered iron-dependent form of cell death, contributes to various
pathologies; however, the prognostic value of ferroptosis-related genes (FRGs) in cervical …

[HTML][HTML] Ferroptosis Driver SOCS1 and Suppressor FTH1 Independently Correlate With M1 and M2 Macrophage Infiltration in Head and Neck Squamous Cell …

ZW Hu, YH Wen, RQ Ma, L Chen, XL Zeng… - Frontiers in Cell and …, 2021 - frontiersin.org
Objective To investigate the role of ferroptosis, an iron-dependent form of non-apoptotic cell
death, in the head and neck squamous cell carcinoma (HNSCC) immune microenvironment …

[HTML][HTML] Single-cell transcriptomics uncover the key ferroptosis regulators contribute to cancer progression in head and neck squamous cell carcinoma

F Liu, L Tang, Q Li, L Chen, Y Pan, Z Yin… - Frontiers in Molecular …, 2022 - frontiersin.org
The mechanism underlying the association between the development of head and neck
squamous cell carcinoma (HNSCC) and ferroptosis is unclear. We analyzed the …

Systematic Construction and Validation of a Novel Ferroptosis‐Related Gene Model for Predicting Prognosis in Cervical Cancer

W Qin, C He, D Jiang, Y Gao, Y Chen… - Journal of …, 2022 - Wiley Online Library
Background and Purpose. Ferroptosis, a mechanism of cell death that is iron‐dependent,
participates in various pathologies of cancer (CC). Nevertheless, the specific function that …

[HTML][HTML] Multi-omics analysis of cancer cell lines with high/low ferroptosis scores and development of a ferroptosis-related model for multiple cancer types

G Shan, H Zhang, G Bi, Y Bian, J Liang… - Frontiers in cell and …, 2021 - frontiersin.org
Background: Ferroptosis is a newly identified regulated cell death characterized by iron-
dependent lipid peroxidation and subsequent membrane oxidative damage, which has …

[HTML][HTML] Ferroptosis-related long non-coding RNA signature contributes to the prediction of prognosis outcomes in head and neck squamous cell carcinomas

W Jiang, Y Song, Z Zhong, J Gao, X Meng - Frontiers in genetics, 2021 - frontiersin.org
Background: Head and neck squamous cell carcinoma (HNSCC) is a malignant tumor,
which makes the prognosis prediction challenging. Ferroptosis is an iron-dependent form of …

Identification of a ferroptosis-associated gene signature and the related therapeutic targets in head and neck squamous carcinoma

Z Huang, Y Li, W Hong, X Chen, Y Pan, Y Weng… - International …, 2022 - Elsevier
Background Head and neck squamous cell carcinoma (HNSCC) has a poor prognosis due
to its high rates of recurrence and metastasis. Herein, we designed and validated an …