[PDF][PDF] Memory T cells represent the predominant lymphocyte subset in acute and chronic liver inflammation

R Volpes, JJ van den Oord, VJ Desmet - Hepatology, 1991 - Wiley Online Library
T cells can be divided into two main phenotypic subpopulations–ie, the CD45RA‐positive
(2H4‐positive)“naive” subset and the CD45RO‐positive (UCHL1‐positive)“memory” subset …

[PDF][PDF] Blood and liver‐infiltrating lymphocytes in primary biliary cirrhosis: increase in activated T and natural killer cells and recruitment of primed memory T cells

A Björkland, R Festin, I Mendel‐Hartvig, A Nyberg… - …, 1991 - Wiley Online Library
We used two‐color and three‐color flow cytometric analysis to study phenotypical activation
and functional subsets of T and natural killer cells in the blood and liver tissue of patients …

Hepatic and peripheral T-lymphocyte patterns in patients with chronic hepatitis C infection: what correlation with histological activity?

A Perrella, O Perrella, C Sbreglia, P Conca… - International Journal …, 2001 - europepmc.org
The immunopathological processes involved in hepatic damage during chronic hepatitis C
infection are not fully understood. Several works suggest the role of T helper 1 (Th1) immune …

The Clinical Significance of Hepatic CD69+CD103+CD8+ Resident‐Memory T Cells in Autoimmune Hepatitis

Z You, Y Li, Q Wang, Z Zhao, Y Li, Q Qian, B Li… - …, 2021 - Wiley Online Library
Background and Aims The diverse inflammatory response found in the liver of patients with
autoimmune hepatitis (AIH) is well established, but identification of potentially pathogenic …

Naive and memory T lymphocytes migrate in comparable numbers through normal rat liver: activated T cells accumulate in the periportal field

B Luettig, L Pape, U Bode, EB Bell… - The Journal of …, 1999 - journals.aai.org
Although the liver is known to contain a significant number of lymphocytes, migration of
these through the compartments of the liver, parenchyma and periportal field, has not been …

Phenotypical analysis and cytokine release of liver‐infiltrating and peripheral blood T lymphocytes from patients with chronic hepatitis of different etiology

HF Löhr, JF Schlaak, G Gerken, B Fleischer, HP Dienes… - Liver, 1994 - Wiley Online Library
Cytokines released by infiltrating T cells may contribute to the hepatic injury in chronic
hepatitis. Therefore, we characterized peripheral blood‐and liver‐infiltrating T cells from …

Resident human hepatitis lymphocytes are phenotypically different from circulating lymphocytes

S Norris, C Collins, DG Doherty, F Smith, G McEntee… - Journal of …, 1998 - Elsevier
Background/Aims: Murine and human studies have documented the existence of
subpopulations of lymphocytes in particular tissues that differ phenotypically and functionally …

Naive and memory T cell infiltrates in chronic hepatitis C: phenotypic changes with interferon treatment

K Imada, Y Fukuda, Y Koyama, I Nakano… - Clinical & …, 1997 - Wiley Online Library
The phenotypes of infiltrating lymphocytes in liver with chronic hepatitis C, including
changes associated with interferon (IFN) treatment, were characterized. Specimens …

Differentiation-dependent and subset-specific recruitment of T-helper cells into murine liver

K Klugewitz, SA Topp, U Dahmen, T Kaiser, S Sommer… - Hepatology, 2002 - Elsevier
It has been suggested that the liver traps and deletes activated and potentially harmful T
cells, especially of the CD8+ subset, providing mechanisms to limit systemic immune …

Two-dimensional flow cytometric analysis of intrahepatic lymphocyte subsets from patients with chronic hepatitis

T Takehara, N Hayashi, K Katayama… - Digestive diseases and …, 1991 - Springer
Peripheral and intrahepatic lymphocyte subsets were analyzed in 22 patients with chronic
hepatitis by two-dimensional flow cytometry. Activated T cells in the liver significantly …