Diethyl phosphate disrupts hypothalamus-pituitary-adrenal axis endocrine hormones via nuclear receptors GR and Nur77: Integration of evidences from in vivo, in …

F Yang, Y Li, Y Xie, W Yao, F Ren - Science of The Total Environment, 2022 - Elsevier
Plenty of population epidemiology and cohort studies have found dialkyl phosphates (DAPs)
in the urine were related to endocrine hormone disorders. However, we did not know …

[HTML][HTML] Assessment of the endocrine-disrupting effects of diethyl phosphate, a nonspecific metabolite of organophosphorus pesticides, by in vivo and in silico …

FW Yang, GP Zhao, FZ Ren, GF Pang, YX Li - Environment International, 2020 - Elsevier
Organophosphorus pesticides (OPs) remain one of the most commonly used pesticides, and
their detection rates and residues in agricultural products, foods and environmental samples …

[HTML][HTML] Effects of diethyl phosphate, a non-specific metabolite of organophosphorus pesticides, on serum lipid, hormones, inflammation, and gut microbiota

F Yang, J Li, G Pang, F Ren, B Fang - Molecules, 2019 - mdpi.com
Organophosphorus pesticides (OPs) can be metabolized to diethyl phosphate (DEP) in the
gut environment, which may affect the immune and endocrine systems and the microbiota …

Assessment of the endocrine-disrupting effects of organophosphorus pesticide triazophos and its metabolites on endocrine hormones biosynthesis, transport and …

FW Yang, YX Li, FZ Ren, J Luo, GF Pang - Food and chemical toxicology, 2019 - Elsevier
Triazophos (TAP) was a widely used organophosphorus insecticide in developing countries.
TAP could produce specific metabolites triazophos-oxon (TAPO) and 1-phenyl-3-hydroxy-1 …

Association of urinary organophosphate esters level with sex steroid hormones levels in adult males: a nationwide study, NHANES 2013–2014

Z Chen, S Qiu, C Zhang, Y Zhan, L Liu, Y Bao… - …, 2022 - Wiley Online Library
Background Exposure to environmental pollution via different mechanisms is associated
with multiple endocrine dysfunctions. Organophosphate esters (OPEs) are endocrine …

[HTML][HTML] The associations between organophosphate esters and urinary incontinence in the general US population

M He, K Jin, S Qiu, X Liao, X Zheng, Z Chen… - … Science and Pollution …, 2022 - Springer
Organophosphate esters (OPEs) impact health in many ways. Since its relationship with
urinary incontinence remains unknown, we aimed to explore their associations in the US …

Endocrine disrupting toxicity of aryl organophosphate esters and mode of action

W Hu, P Gao, L Wang, J Hu - Critical Reviews in Environmental …, 2023 - Taylor & Francis
Organophosphate esters (OPEs) are frequently detected in the environment and human
samples, bringing potential adverse effects to ecosystems and human health. Aryl OPEs …

Triazophos and its metabolite diethyl phosphate have different effects on endocrine hormones and gut health in rats

FW Yang, B Fang, GF Pang, M Zhang… - … Science and Health …, 2021 - Taylor & Francis
Organophosphorus pesticide (OP) residues present in food can be metabolized into
diethylphosphate (DEP) in vivo. Epidemiological studies of OPs have usually focused on …

[HTML][HTML] Comparison of the mechanisms of estrogen disrupting effects between triphenyl phosphate (TPhP) and tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP)

X Ji, N Li, M Ma, X Li, K Zhu, K Rao, Z Wang… - Ecotoxicology and …, 2022 - Elsevier
As the typical aryl-organophosphate flame retardants (OPFRs), triphenyl phosphate (TPhP)
and tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) were reported to be estrogen …

In Vivo Characterization of the Toxicological Properties of DPhP, One of the Main Degradation Products of Aryl Phosphate Esters

S Selmi-Ruby, J Marín-Sáez, A Fildier… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Aryl phosphate esters (APEs) are widely used and commonly present in the
environment. Health hazards associated with these compounds remain largely unknown …