pH-triggered polypeptides nanoparticles for efficient BODIPY imaging-guided near infrared photodynamic therapy

L Liu, L Fu, T Jing, Z Ruan, L Yan - ACS Applied Materials & …, 2016 - ACS Publications
An efficient pH-responsive multifunctional polypeptide micelle for simultaneous imaging and
in vitro photodynamic therapy (PDT) has been prepared. The goal here is to detect and treat …

Near infrared imaging-guided photodynamic therapy under an extremely low energy of light by galactose targeted amphiphilic polypeptide micelle encapsulating …

L Liu, Z Ruan, T Li, P Yuan, L Yan - Biomaterials science, 2016 - pubs.rsc.org
Near infrared (NIR) imaging-guided photodynamic therapy (PDT) is attractive, especially the
utilization of one dye as both a photosensitizer and fluorescent probe, and the as …

Oxygen self-sufficient fluorinated polypeptide nanoparticles for NIR imaging-guided enhanced photodynamic therapy

P Yuan, Z Ruan, W Jiang, L Liu, J Dou, T Li… - Journal of Materials …, 2018 - pubs.rsc.org
A major hindrance for photodynamic therapy (PDT) to achieve higher efficiency is the
hypoxia environment in the tumor area and the PDT-induced continuous consumption of …

High singlet oxygen yield photosensitizer based polypeptide nanoparticles for low-power near-infrared light imaging-guided photodynamic therapy

Z Ruan, W Miao, P Yuan, L Le, L Jiao… - Bioconjugate …, 2018 - ACS Publications
NIR photosensitizer is attractive for photodynamic therapy (PDT). Low-power light irradiation
and imaging-guided PDT makes it possible to increase tissue penetration depth. The pyrrole …

Self-quenching synthesis of coordination polymer pre-drug nanoparticles for selective photodynamic therapy

Y Song, Y Li, Y Zhang, L Wang, Z Xie - Journal of Materials Chemistry …, 2019 - pubs.rsc.org
The design and preparation of a photoactive coordination polymer nanoplatform with tumor-
related stimuli-activatability and biodegradability is highly desirable for achieving highly …

Amino modified iodinated BODIPY photosensitizer for highly efficient NIR imaging-guided photodynamic therapy with ultralow dose

Y Tian, Q Cheng, H Dang, H Qian, C Teng, K Xie… - Dyes and …, 2021 - Elsevier
In PDT, high doses of photosensitizers can lead to prolonged patient photosensitivity and
undesired side effects. As a classic fluorescent dye, BODIPY has attracted much attention in …

NIR imaging-guided combined photodynamic therapy and chemotherapy by a pH-responsive amphiphilic polypeptide prodrug

Z Ruan, L Liu, W Jiang, S Li, Y Wang, L Yan - Biomaterials science, 2017 - pubs.rsc.org
pH-Sensitive doxorubicin conjugated polymeric micelles entrapped with near infrared (NIR)
photosensitizer BODIPY (which works as an imaging agent at the same time) were designed …

A BODIPY-modified polymeric micelle for sustaining enhanced photodynamic therapy

YC Zhang, L She, ZY Xu, ZK Wang, Z Ma, F Yang… - Chinese Chemical …, 2022 - Elsevier
Photodynamic therapy (PDT) has been gaining popularity in both scientific research and
clinic applications due to its non-invasiveness and spatiotemporal targeting properties …

Ultralow-power near infrared lamp light operable targeted organic nanoparticle photodynamic therapy

L Huang, Z Li, Y Zhao, Y Zhang, S Wu… - Journal of the …, 2016 - ACS Publications
Tissue penetration depth is a major challenge in practical photodynamic therapy (PDT). A
biocompatible and highly effective near infrared (NIR)-light-absorbing carbazole-substituted …

Red fluorescent BODIPY-based nanoparticles for targeted cancer imaging-guided photodynamic therapy

C Kim, DK Mai, WJ Kim, IW Badon, J Jo, D Kang… - Biomaterials …, 2024 - pubs.rsc.org
Imaging-guided diagnosis and treatment of cancer hold potential to significantly improve
therapeutic accuracies and efficacies. Central to this theragnostic approach has been the …