Systemic lupus erythematosus, regulatory T cells and pregnancy

S Varghese, I Crocker, IN Bruce… - Expert review of clinical …, 2011 - Taylor & Francis
Systemic lupus erythematosus (SLE) is the most common autoimmune disease affecting
women of reproductive age and is associated with poor maternal and fetal outcomes. CD4+ …

SLE and pregnancy: the potential role for regulatory T cells

C Tower, I Crocker, D Chirico, P Baker… - Nature Reviews …, 2011 - nature.com
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that
disproportionally affects women, especially in their reproductive years. SLE is associated …

A decreased number of circulating regulatory T cells is associated with adverse pregnancy outcomes in patients with systemic lupus erythematosus

HT Li, SX Zhang, JQ Zhang, T Cheng… - Immunity …, 2022 - Wiley Online Library
Objective As an autoimmune disease affecting women of reproductive age, systemic lupus
erythematosus (SLE) is linked to adverse fetal and maternal outcomes. However, the status …

Regulatory T cells in systemic lupus erythematosus and pregnancy

C Tower, S Mathen, I Crocker… - American Journal of …, 2013 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disorder that
predominantly affects women of reproductive age. As clinical outcomes improve, pregnancy …

The dynamics of Th17/Treg ratio in SLE patients during pregnancy

A Braga, E Neves, J Guimarães, J Braga… - Journal of Reproductive …, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder that affects
women at childbearing age. During pregnancy, maternal immune system is challenged to …

[PDF][PDF] T regulatory cells: regulating both term and preterm labor?

N Gomez‐Lopez, E Laresgoiti‐Servitje - Immunology and Cell …, 2012 - academia.edu
Pregnancy is a beautiful example of immunological regulation, where several changes
occur in the immune system of the mother that allow her to tolerate the fetus, a semi …

Mechanisms involved in the expansion of Tregs during pregnancy: role of IL-2/STAT5 signalling

L Fainboim, L Arruvito - Journal of reproductive immunology, 2011 - Elsevier
Several studies have reported that the fine-tuning of regulatory T cells (Tregs) is required for
a successful pregnancy and for the control of autoimmune diseases. Here, we review the …

Regulatory T cells and their role in pregnancy

A Leber, A Teles, AC Zenclussen - American journal of …, 2010 - Wiley Online Library
Citation Leber A, Teles A, Zenclussen AC. Regulatory T cells and their role in pregnancy.
Am J Reprod Immunol 2010 Regulatory T cells emerge in the last years as key players in …

Pregnancy-associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs

A Steinborn, E Schmitt, A Kisielewicz… - Clinical & …, 2012 - academic.oup.com
Dysregulations concerning the composition and function of regulatory T cells (Tregs) are
assumed to be involved in the pathophysiology of complicated pregnancies. We used six …

Regulatory T cells show dynamic behavior during late pregnancy, delivery, and the postpartum period

J Lima, C Martins, G Nunes, MJ Sousa… - Reproductive …, 2017 - journals.sagepub.com
Regulatory T cells (Tregs) are critical immunomodulators during early pregnancy by
preventing maternal T-cell activation against fetal cells. However, how populations of …