Drug interactions of clinical importance with antihyperglycaemic agents: an update

AJ Scheen - Drug safety, 2005 - Springer
Because management of type 2 diabetes mellitus usually involves combined
pharmacological therapy to obtain adequate glucose control and treatment of concurrent …

Clinically and pharmacologically relevant interactions of antidiabetic drugs

M May, C Schindler - Therapeutic advances in endocrinology …, 2016 - journals.sagepub.com
Patients with type 2 diabetes mellitus often require multifactorial pharmacological treatment
due to different comorbidities. An increasing number of concomitantly taken medications …

Antihyperglycaemic agents: drug interactions of clinical importance

AJ Scheen, PJ Lefèbvre - Drug safety, 1995 - Springer
Summary Non-insulin-dependent (type 2) diabetes mellitus (NIDDM) affects middle-aged or
elderly people who frequently have several other concomitant diseases, especially obesity …

Drug interactions with oral antidiabetic agents: pharmacokinetic mechanisms and clinical implications

A Tornio, M Niemi, PJ Neuvonen… - Trends in pharmacological …, 2012 - cell.com
There is a growing epidemic of type 2 diabetes (T2DM), and it is associated with various
comorbidities. Patients with T2DM are usually treated with multiple drugs, and are therefore …

Pharmacotherapy of type 2 diabetes mellitus: an update on drug–drug interactions

M Amin, N Suksomboon - Drug safety, 2014 - Springer
The incidence of type 2 diabetes mellitus is increasing rapidly, as are the associated co-
morbidities. Consequently, it has become necessary for a diabetic patient to take multiple …

Combining sulfonylureas and other oral agents

M Riddle - The American journal of medicine, 2000 - Elsevier
Type 2 diabetes mellitus is a progressive disorder, and although oral monotherapy is often
initially successful, it is associated with a high secondary failure rate, which contributes to …

A comprehensive review of drug–drug interactions with metformin

TB Stage, K Brøsen, MMH Christensen - Clinical pharmacokinetics, 2015 - Springer
Metformin is the world's most commonly used oral glucose-lowering drug for type 2 diabetes,
and this is mainly because it protects against diabetes-related mortality and all-cause …

Oral hypoglycemic agents: insulin secretagogues, α-glucosidase inhibitors and insulin sensitizers

SA Raptis, GD Dimitriadis - Experimental and Clinical …, 2001 - thieme-connect.com
In this review we present the agents that are in use in the treatment of type 2 diabetes.
Sulfonylureas of the 1 st and 2 nd generation increase insulin secretion but can induce …

Drug interactions with lipid‐lowering drugs: mechanisms and clinical relevance

PJ Neuvonen, M Niemi… - Clinical Pharmacology & …, 2006 - Wiley Online Library
Lipid‐lowering drugs, especially 3‐hydroxy‐3‐methylglutaryl–coenzyme A inhibitors
(statins), are widely used in the treatment and prevention of atherosclerotic disease. The …

Oral antidiabetic drug metabolism: pharmacogenomics and drug interactions

A Holstein, W Beil - Expert opinion on drug metabolism & …, 2009 - Taylor & Francis
Background: Type 2 diabetes is progressive in nature and so to control cardiovascular risk,
most patients need combinations of oral antidiabetic drugs (OADs) plus or minus insulin …