Future perspectives in pulmonary arterial hypertension
LJ Rubin - Pulmonary Vascular Disorders, 2012 - karger.com
In a remarkably short interval of time, pulmonary artery hypertension (PAH) has evolved from
a disease of unknown pathogenesis devoid of effective therapy to a condition whose cellular …
a disease of unknown pathogenesis devoid of effective therapy to a condition whose cellular …
[HTML][HTML] Pulmonary arterial hypertension: Emerging principles of precision medicine across basic science to clinical practice
NJ Kelly, SY Chan - Reviews in cardiovascular medicine, 2022 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is an enigmatic and deadly vascular disease with no
known cure. Recent years have seen rapid advances in our understanding of the molecular …
known cure. Recent years have seen rapid advances in our understanding of the molecular …
Pathobiology of pulmonary arterial hypertension: understanding the roads less travelled
AR Hemnes, M Humbert - European Respiratory Review, 2017 - Eur Respiratory Soc
The pathobiology of pulmonary arterial hypertension (PAH) is complex and incompletely
understood. Although three pathogenic pathways have been relatively well characterised, it …
understood. Although three pathogenic pathways have been relatively well characterised, it …
The emergence of new therapeutic targets in pulmonary arterial hypertension: from now to the near future
S Malenfant, G Margaillan, JE Loehr… - Expert Review of …, 2013 - Taylor & Francis
Pulmonary arterial hypertension (PAH) is a vascular remodeling disease that pathologically
increases pulmonary vascular resistance. Ultimately, this leads to right ventricular failure …
increases pulmonary vascular resistance. Ultimately, this leads to right ventricular failure …
Pulmonary arterial hypertension: pathophysiology and treatment
NSH Lan, BD Massam, SS Kulkarni, CC Lang - Diseases, 2018 - mdpi.com
Pulmonary arterial hypertension (PAH), the first category of pulmonary hypertension, is a
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …
Future perspectives in pulmonary arterial hypertension
G Simonneau, MM Hoeper… - European …, 2016 - Eur Respiratory Soc
While there have been advances in the field of pulmonary arterial hypertension (PAH),
disease management remains suboptimal for many patients. The development of novel …
disease management remains suboptimal for many patients. The development of novel …
Clinical trial design and new therapies for pulmonary arterial hypertension
O Sitbon, M Gomberg-Maitland… - European …, 2019 - Eur Respiratory Soc
Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on
case reports and small series, and was largely ineffectual. As a deeper understanding of the …
case reports and small series, and was largely ineffectual. As a deeper understanding of the …
Emerging therapies and future directions in pulmonary arterial hypertension
V Gurtu, ED Michelakis - Canadian Journal of Cardiology, 2015 - Elsevier
Pulmonary arterial hypertension (PAH) is a complex obliterative vascular disease. It remains
deadly despite an explosion of basic research over the past 20 years that identified myriads …
deadly despite an explosion of basic research over the past 20 years that identified myriads …
The potential application and promising role of targeted therapy in pulmonary arterial hypertension
MCW Hsieh, WT Wang, JL Yeh, CY Lin, YR Kuo… - Biomedicines, 2022 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare yet serious progressive disorder that is
currently incurable. This female-predominant disease unfolds as a pan-vasculopathy that …
currently incurable. This female-predominant disease unfolds as a pan-vasculopathy that …
Promising therapeutic approaches in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a debilitating multifactorial disease characterized
by progressive pulmonary vascular remodeling, elevated pulmonary arterial pressure, and …
by progressive pulmonary vascular remodeling, elevated pulmonary arterial pressure, and …