Bleeding and ischemic risk prediction in patients with high bleeding risk (an EVOLVE short DAPT analysis)

N Mihatov, AJ Kirtane, R Stoler, R Feldman… - The American journal of …, 2023 - Elsevier
The EVOLVE Short DAPT study demonstrated the safety of truncated dual antiplatelet
therapy (DAPT) in patients with a high bleeding risk (HBR) treated with SYNERGY stent …

Clinical impact of extended dual antiplatelet therapy after percutaneous coronary interventions in the drug-eluting stent era: a meta-analysis of randomized trials

S Cassese, RA Byrne, T Tada, LA King… - European heart …, 2012 - academic.oup.com
Aims The aim of this study was to evaluate benefits and risks of extending dual antiplatelet
therapy (DAPT) after percutaneous coronary intervention (PCI) in the drug-eluting stent era …

Pooled Analysis of Bleeding, Major Adverse Cardiovascular Events, and all‐Cause Mortality in Clinical Trials of Time‐Constrained Dual‐Antiplatelet Therapy after …

JD McClure, JC Ramsay, C Berry - Journal of the American Heart …, 2020 - Am Heart Assoc
Background The net clinical benefit of dual antiplatelet therapy (DAPT) reflects the
paradoxical effects of an increased risk of bleeding and a reduced risk of major adverse …

Short‐versus long‐term Dual Antiplatelet therapy after drug‐eluting stent implantation in women versus men: A sex‐specific patient‐level pooled‐analysis of six …

FJ Sawaya, MC Morice, M Spaziano… - Catheterization and …, 2017 - Wiley Online Library
Background Whether the efficacy and safety of dual antiplatelet therapy (DAPT) are uniform
between sexes is unclear. We sought to compare clinical outcomes between short‐(≤ 6 …

De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and …

L Pasea, SC Chung, M Pujades-Rodriguez… - European heart …, 2017 - academic.oup.com
Aims The aim of this study is to develop models to aid the decision to prolong dual
antiplatelet therapy (DAPT) that requires balancing an individual patient's potential benefits …

Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: results from the Clopidogrel for …

PB Berger, DL Bhatt, V Fuster, PG Steg, KAA Fox… - Circulation, 2010 - Am Heart Assoc
Background—Uncertainty exists about the frequency, correlates, and clinical significance of
bleeding with dual antiplatelet therapy (DAPT), particularly over an extended period in a …

Thirty-days versus longer duration of dual antiplatelet treatment after percutaneous coronary interventions with newer drug-eluting stents: a systematic review and …

G Tsigkas, A Apostolos, DD Chlorogiannis, E Bousoula… - Life, 2023 - mdpi.com
Abbreviation of the duration of dual antiplatelet therapy (DAPT)(one or three months) has
been recently proposed, especially for high bleeding risk patients, after percutaneous …

Derivation and validation of the predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT …

F Costa, D Van Klaveren, S James, D Heg, L Räber… - The Lancet, 2017 - thelancet.com
Background Dual antiplatelet therapy (DAPT) with aspirin plus a P2Y 12 inhibitor prevents
ischaemic events after coronary stenting, but increases bleeding. Guidelines support …

Bleeding-related deaths in relation to the duration of dual-antiplatelet therapy after coronary stenting

T Palmerini, L Bacchi Reggiani, D Della Riva… - Journal of the American …, 2017 - jacc.org
Background: Although some randomized controlled trials (RCTs) and meta-analyses have
suggested that prolonged dual-antiplatelet therapy (DAPT) may be associated with …