[PDF][PDF] Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy
F Mollinedo, C Vandier - 2016 - researchgate.net
Paul-Alain Jaffrès a, e, Consuelo Gajate b, Ana Maria Bouchet c, e, Hélène Couthon-
Gourvès a, e, Aurélie Chantôme c, e, Marie Potier-Cartereau c, e, Pierre Besson c, e …
Gourvès a, e, Aurélie Chantôme c, e, Marie Potier-Cartereau c, e, Pierre Besson c, e …
Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy
PA Jaffres, C Gajate, AM Bouchet… - Pharmacology & …, 2016 - Elsevier
Synthetic alkyl lipids, such as the ether lipids edelfosine (1-O-octadecyl-2-O-methyl-rac-
glycero-3-phosphocholine) and ohmline (1-O-hexadecyl-2-O-methyl-rac-glycero-3-β …
glycero-3-phosphocholine) and ohmline (1-O-hexadecyl-2-O-methyl-rac-glycero-3-β …
Edelfosine and miltefosine effects on lipid raft properties: membrane biophysics in cell death by antitumor lipids
BM Castro, A Fedorov, V Hornillos… - The Journal of …, 2013 - ACS Publications
Edelfosine (1-O-octadecyl-2-O-methyl-sn-glycero-phosphocholine) and miltefosine (
hexadecylphosphocholine) are synthetic alkylphospholipids (ALPs) that are reported to …
hexadecylphosphocholine) are synthetic alkylphospholipids (ALPs) that are reported to …
Lipid rafts as major platforms for signaling regulation in cancer
F Mollinedo, C Gajate - Advances in biological regulation, 2015 - Elsevier
Cell signaling does not apparently occur randomly over the cell surface, but it seems to be
integrated very often into cholesterol-rich membrane domains, termed lipid rafts. Membrane …
integrated very often into cholesterol-rich membrane domains, termed lipid rafts. Membrane …
[PDF][PDF] Lipid raft platforms as major scaffolds in regulating apoptotic signaling
F Mollinedo - SEBBM - congresos.sebbm.es
Membrane lipid rafts are highly ordered membrane domains enriched in cholesterol,
sphingolipids and gangliosides, which form specialized domains with distinct composition …
sphingolipids and gangliosides, which form specialized domains with distinct composition …
Lipids and membrane microdomains: the glycerolipid and alkylphosphocholine class of cancer chemotherapeutic drugs
V Zaremberg, S Ganesan, M Mahadeo - Lipid Signaling in Human …, 2020 - Springer
Synthetic antitumor lipids are metabolically stable lysophosphatidylcholine derivatives,
encompassing a class of non-mutagenic drugs that selectively target cancerous cells. In this …
encompassing a class of non-mutagenic drugs that selectively target cancerous cells. In this …
Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine
C Gajate, F Mollinedo - Anti-Cancer Agents in Medicinal …, 2014 - ingentaconnect.com
The so-called alkylphospholipid analogs (APLs) constitute a family of synthetic antitumor
compounds that target cell membranes. The ether phospholipid edelfosine has been …
compounds that target cell membranes. The ether phospholipid edelfosine has been …
Mitochondrial targeting involving cholesterol-rich lipid rafts in the mechanism of action of the antitumor ether lipid and alkylphospholipid analog edelfosine
F Mollinedo, C Gajate - Pharmaceutics, 2021 - mdpi.com
The ether lipid edelfosine induces apoptosis selectively in tumor cells and is the prototypic
molecule of a family of synthetic antitumor compounds collectively known as …
molecule of a family of synthetic antitumor compounds collectively known as …
Cluster of apoptotic signaling molecule-enriched rafts (CASMER) as a new target in the mechanism of action of the antitumor alkylphospholipid analogue edelfosine …
Lipid rafts are cholesterol-and sphingolipid-rich liquid ordered microdomains that float within
the liquid disordered bilayer in cell membranes, and can coalesce upon clustering of their …
the liquid disordered bilayer in cell membranes, and can coalesce upon clustering of their …
Lipid rafts: integrated platforms for vascular organization offering therapeutic opportunities
Research on the nanoscale membrane structures known as lipid rafts is relevant to the fields
of cancer biology, inflammation and ischaemia. Lipid rafts recruit molecules critical to …
of cancer biology, inflammation and ischaemia. Lipid rafts recruit molecules critical to …
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