A series of 59 chalcones was prepared and evaluated for the antimitotic effect against K562
leukemia cells. The most active chalcones were evaluated for their antiproliferative activity …

Chalcones belong to the flavonoid class of phenolic compounds. They form one of the
largest groups of bioactive natural products. The potential anticancer, anti-inflammatory …

Introduction: Chalcones are one of the major classes of naturally occurring compounds. A
large number of synthetic routes have been reported for the synthesis of chalcones, the most …

There is an emerging paradigm shift in oncology that seeks to emphasize molecularly
targeted approaches for cancer prevention and therapy. Chalcones (1, 3-diphenyl-2-propen …

Chalcones are secondary metabolites belonging to the flavonoid (C6-C3-C6 system) family
that are ubiquitous in edible and medicinal plants, and they are bioprecursors of plant …

Chalcones are polyketide natural products that display various biological activities, including
anticancer properties. Compelling data from laboratory studies indicate that chalcones have …

Introduction: Chalcones are a group of plant-derived polyphenolic compounds belonging to
the flavonoids family that possess a wide variety of cytoprotective and modulatory functions …

Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …

Chalcone derivatives are considered valuable species because they possess a
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …

Chalcones, aromatic ketones and enones acting as the precursor for flavonoids such as
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …