Synthesis of chalcones derivatives and their biological activities: a review
NAA Elkanzi, H Hrichi, RA Alolayan, W Derafa… - ACS …, 2022 - ACS Publications
Chalcone derivatives are considered valuable species because they possess a
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …
Heterocyclic chalcone analogues as potential anticancer agents
Chalcones, aromatic ketones and enones acting as the precursor for flavonoids such as
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …
An updated patent review of therapeutic applications of chalcone derivatives (2014-present)
Introduction: Chalcone or benzylideneacetophenone or 1, 3-diphenyl-2-propene-1-one is a
natural product comprising of two aromatic rings connected together by a three-carbon α, β …
natural product comprising of two aromatic rings connected together by a three-carbon α, β …
Chalcones as promising lead compounds on cancer therapy
AJ Leon-Gonzalez, N Acero… - Current medicinal …, 2015 - ingentaconnect.com
Chalcones constitute a group of phenolic compounds that command an increasing interest
on cancer research. Natural chalcones are widespread through the plant kingdom. The most …
on cancer research. Natural chalcones are widespread through the plant kingdom. The most …
An update on antitumor activity of naturally occurring chalcones
EH Zhang, RF Wang, SZ Guo… - … Based Complementary and …, 2013 - Wiley Online Library
Chalcones, which have characteristic 1, 3‐diaryl‐2‐propen‐1‐one skeleton, are mainly
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …
Therapeutic potential of chalcones as cardiovascular agents
DK Mahapatra, SK Bharti - Life sciences, 2016 - Elsevier
Cardiovascular diseases are the leading cause of death affecting 17.3 million people across
the globe and are estimated to affect 23.3 million people by year 2030. In recent years …
the globe and are estimated to affect 23.3 million people by year 2030. In recent years …
Heteroaryl chalcones: Mini review about their therapeutic voyage
B Mathew, J Suresh, S Anbazghagan, J Paulraj… - … & Preventive Nutrition, 2014 - Elsevier
Various structural modifications of the heteroaryl chalcones templates have been made to
explore its promising biological potential in recent years. This review article is an effort to …
explore its promising biological potential in recent years. This review article is an effort to …
[HTML][HTML] Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects
J Higgs, C Wasowski, A Marcos, M Jukič, CH Paván… - Heliyon, 2019 - cell.com
Anxiety disorders, depression and pain are highly prevalent pathologies. Their
pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to …
pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to …
Naturally occurring chalcones and their biological activities
The aim of this review is to summarize the various naturally occurring chalcone compounds
which have been isolated from different plants. Chalcones considered as obligate …
which have been isolated from different plants. Chalcones considered as obligate …
Chalcones derivatives acting as cell cycle blockers: potential anti cancer drugs?
A Boumendjel, X Ronot, J Boutonnat - Current drug targets, 2009 - ingentaconnect.com
Chalcones (1, 3-diphenylpropen-1-ones) are naturally occurring compounds belonging to
the flavonoid family and are largely investigated in various therapeutic area and especially …
the flavonoid family and are largely investigated in various therapeutic area and especially …