Synthesis of chalcones derivatives and their biological activities: a review

NAA Elkanzi, H Hrichi, RA Alolayan, W Derafa… - ACS …, 2022 - ACS Publications
Chalcone derivatives are considered valuable species because they possess a
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …

Heterocyclic chalcone analogues as potential anticancer agents

V Sharma, V Kumar, P Kumar - Anti-Cancer Agents in Medicinal …, 2013 - ingentaconnect.com
Chalcones, aromatic ketones and enones acting as the precursor for flavonoids such as
Quercetin, are known for their anticancer effects. Although, parent chalcones consist of two …

An updated patent review of therapeutic applications of chalcone derivatives (2014-present)

D Kar Mahapatra, V Asati, SK Bharti - Expert opinion on therapeutic …, 2019 - Taylor & Francis
Introduction: Chalcone or benzylideneacetophenone or 1, 3-diphenyl-2-propene-1-one is a
natural product comprising of two aromatic rings connected together by a three-carbon α, β …

Chalcones as promising lead compounds on cancer therapy

AJ Leon-Gonzalez, N Acero… - Current medicinal …, 2015 - ingentaconnect.com
Chalcones constitute a group of phenolic compounds that command an increasing interest
on cancer research. Natural chalcones are widespread through the plant kingdom. The most …

An update on antitumor activity of naturally occurring chalcones

EH Zhang, RF Wang, SZ Guo… - … Based Complementary and …, 2013 - Wiley Online Library
Chalcones, which have characteristic 1, 3‐diaryl‐2‐propen‐1‐one skeleton, are mainly
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …

Therapeutic potential of chalcones as cardiovascular agents

DK Mahapatra, SK Bharti - Life sciences, 2016 - Elsevier
Cardiovascular diseases are the leading cause of death affecting 17.3 million people across
the globe and are estimated to affect 23.3 million people by year 2030. In recent years …

Heteroaryl chalcones: Mini review about their therapeutic voyage

B Mathew, J Suresh, S Anbazghagan, J Paulraj… - … & Preventive Nutrition, 2014 - Elsevier
Various structural modifications of the heteroaryl chalcones templates have been made to
explore its promising biological potential in recent years. This review article is an effort to …

[HTML][HTML] Chalcone derivatives: synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects

J Higgs, C Wasowski, A Marcos, M Jukič, CH Paván… - Heliyon, 2019 - cell.com
Anxiety disorders, depression and pain are highly prevalent pathologies. Their
pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to …

Naturally occurring chalcones and their biological activities

Z Rozmer, P Perjési - Phytochemistry reviews, 2016 - Springer
The aim of this review is to summarize the various naturally occurring chalcone compounds
which have been isolated from different plants. Chalcones considered as obligate …

Chalcones derivatives acting as cell cycle blockers: potential anti cancer drugs?

A Boumendjel, X Ronot, J Boutonnat - Current drug targets, 2009 - ingentaconnect.com
Chalcones (1, 3-diphenylpropen-1-ones) are naturally occurring compounds belonging to
the flavonoid family and are largely investigated in various therapeutic area and especially …