[HTML][HTML] Bioactivities of chalcones

DW Elias, MA Beazely… - Current medicinal …, 1999 - books.google.com
This review outlines the different bioactivities of a variety of chalcones. The cytotoxic,
anticancer, chemopreventative and mutagenic properties of a number of chalcones are …

Synthesis and Pharmacological Activities of Chalcone and Its Derivatives Bearing N-Heterocyclic Scaffolds: A Review

K Mezgebe, Y Melaku, E Mulugeta - ACS omega, 2023 - ACS Publications
The incorporation of heterocyclic moieties into the standard chemical structure with a
biologically active scaffold has become of crucial practice for the construction of …

Dihydrochalcones: Methods of acquisition and pharmacological properties—A first systematic review

M Stompor, D Broda, A Bajek-Bil - Molecules, 2019 - mdpi.com
Dihydrochalcones are a class of secondary metabolites, for which demand in biological and
pharmacological applications is still growing. They posses several health-endorsing …

Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents

BA Bhat, KL Dhar, SC Puri, AK Saxena… - Bioorganic & medicinal …, 2005 - Elsevier
A series of substituted chalcones and their corresponding pyrazoles were synthesized and
evaluated for in vitro cytotoxic activity against a panel of human cancer cell lines. Out of 93 …

Chalcone derivatives: promising starting points for drug design

MN Gomes, EN Muratov, M Pereira, JC Peixoto… - Molecules, 2017 - mdpi.com
Medicinal chemists continue to be fascinated by chalcone derivatives because of their
simple chemistry, ease of hydrogen atom manipulation, straightforward synthesis, and a …

Chalcones and their potential role in inflammation.

C Kontogiorgis, M Mantzanidou… - Mini reviews in …, 2008 - europepmc.org
Chalcones are a group of phenolic compounds which possess a wide variety of
cytoprotective and modulatory functions. They have been shown to possess antioxidant …

Chalcones: synthesis, structure diversity and pharmacological aspects

H Suwito, AN Kristanti… - Journal of chemical and …, 2014 - repository.unair.ac.id
The diverse pharmacological activities of chalcones, such as antioxidant, antimicrobial,
anticancer, and antihepatotoxic, attract many researchers to isolate and elucidate them from …

Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents

MVB Reddy, CR Su, WF Chiou, YN Liu… - Bioorganic & medicinal …, 2008 - Elsevier
The chalcone skeleton (1, 3-diphenyl-2-propen-1-one) is a unique template that is
associated with various biological activities. We synthesized Mannich bases of heterocyclic …

Dietary chalcones with chemopreventive and chemotherapeutic potential

B Orlikova, D Tasdemir, F Golais, M Dicato… - Genes & nutrition, 2011 - Springer
Chalcones are absorbed in the daily diet and appear to be promising cancer
chemopreventive agents. Chalcones represent an important group of the polyphenolic …

Synthesis and biological evaluation of chalcone derivatives (mini review)

S Nasir Abbas Bukhari, M Jasamai… - Mini reviews in …, 2012 - ingentaconnect.com
Chalcones are the principal precursors for the biosynthesis of flavonoids and isoflavonoids.
A three carbon α, β-unsaturated carbonyl system constitutes chalcones. Chalcones are the …