Vasculogenic mimicry, a complex and devious process favoring tumorigenesis–interest in making it a therapeutic target

L Treps, S Faure, N Clere - Pharmacology & therapeutics, 2021 - Elsevier
Tumor cell vasculogenic mimicry (VM), also dubbed vascular mimicry, describes the
plasticity of aggressive cancer cells forming de novo vascular networks and is associated …

Overview of advances in vasculogenic mimicry–a potential target for tumor therapy

H Ge, H Luo - Cancer management and research, 2018 - Taylor & Francis
Vasculogenic mimicry (VM) describes the process utilized by highly aggressive cancer cells
to generate vascular-like structures without the presence of endothelial cells. VM has been …

Advanced research on vasculogenic mimicry in cancer

L Qiao, N Liang, J Zhang, J Xie, F Liu… - Journal of cellular …, 2015 - Wiley Online Library
Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …

Advances and prospects of vasculogenic mimicry in glioma: a potential new therapeutic target?

H Cai, W Liu, X Liu, Z Li, T Feng, Y Xue… - OncoTargets and …, 2020 - Taylor & Francis
Vasculogenic mimicry (VM) is the formation of a “vessel-like” structure without endothelial
cells. VM exists in vascular-dependent solid tumors and is a special blood supply source …

Vasculogenic mimicry in carcinogenesis and clinical applications

Q Luo, J Wang, W Zhao, Z Peng, X Liu, B Li… - Journal of hematology & …, 2020 - Springer
Distinct from classical tumor angiogenesis, vasculogenic mimicry (VM) provides a blood
supply for tumor cells independent of endothelial cells. VM has two distinct types, namely …

The hypoxia-related signaling pathways of vasculogenic mimicry in tumor treatment

S Li, W Meng, Z Guan, Y Guo, X Han - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Tumors require a blood supply for survival, growth, and metastasis. It is widely accepted that
the development of the tumor microcirculation compartment need the production of new …

Physicochemical aspects of the tumour microenvironment as drivers of vasculogenic mimicry

E Andreucci, S Peppicelli, J Ruzzolini… - Cancer and Metastasis …, 2022 - Springer
Tumour vascularisation is vital for cancer sustainment representing not only the main source
of nutrients and oxygen supply but also an escape route for single or clustered cancer cells …

Vasculogenic mimicry: become an endothelial cell “but not so much”

M Fernández-Cortés, D Delgado-Bellido… - Frontiers in …, 2019 - frontiersin.org
Blood vessels supply all body tissues with nutrients and oxygen, take away waste products
and allow the arrival of immune cells and other cells (pericytes, smooth muscle cells) that …

Signalling pathways in vasculogenic mimicry

YWJ Paulis, PMMB Soetekouw, HMW Verheul… - … et Biophysica Acta (BBA …, 2010 - Elsevier
Solid tumour growth is dependent on the development of an adequate blood supply. For
years, sprouting angiogenesis has been considered an exclusive mechanism of tumour …

Vascular mimicry: changing the therapeutic paradigms in cancer

N Fathi Maroufi, S Taefehshokr, MR Rashidi… - Molecular biology …, 2020 - Springer
Cancer is a major problem in the health system, and despite many efforts to effectively treat
it, none has yet been fully successful. Angiogenesis and metastasis are considered as major …