Hippocampal somatostatin interneurons, long-term synaptic plasticity and memory
A distinctive feature of the hippocampal structure is the diversity of inhibitory interneurons.
These complex inhibitory interconnections largely contribute to the tight modulation of …
These complex inhibitory interconnections largely contribute to the tight modulation of …
Disinhibition in learning and memory circuits: New vistas for somatostatin interneurons and long-term synaptic plasticity
J Artinian, JC Lacaille - Brain research bulletin, 2018 - Elsevier
Neural circuit functions involve finely controlled excitation/inhibition interactions that allow
complex neuronal computations and support high order brain functions such as learning …
complex neuronal computations and support high order brain functions such as learning …
Presynaptic GABAB receptors functionally uncouple somatostatin interneurons from the active hippocampal network
Information processing in cortical neuronal networks relies on properly balanced excitatory
and inhibitory neurotransmission. A ubiquitous motif for maintaining this balance is the …
and inhibitory neurotransmission. A ubiquitous motif for maintaining this balance is the …
Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
Astrocytes are important regulators of excitatory synaptic networks. However, astrocytes
regulation of inhibitory synaptic systems remains ill defined. This is particularly relevant …
regulation of inhibitory synaptic systems remains ill defined. This is particularly relevant …
Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes
The signaling diversity of GABAergic interneurons to post-synaptic neurons is crucial to
generate the functional heterogeneity that characterizes brain circuits. Whether this diversity …
generate the functional heterogeneity that characterizes brain circuits. Whether this diversity …
Somatostatin-expressing inhibitory interneurons in cortical circuits
I Yavorska, M Wehr - Frontiers in neural circuits, 2016 - frontiersin.org
Cortical inhibitory neurons exhibit remarkable diversity in their morphology, connectivity, and
synaptic properties. Here, we review the function of somatostatin-expressing (SOM) …
synaptic properties. Here, we review the function of somatostatin-expressing (SOM) …
Somatostatin-positive interneurons in the dentate gyrus of mice provide local-and long-range septal synaptic inhibition
M Yuan, T Meyer, C Benkowitz, S Savanthrapadian… - Elife, 2017 - elifesciences.org
Somatostatin-expressing-interneurons (SOMIs) in the dentate gyrus (DG) control formation
of granule cell (GC) assemblies during memory acquisition. Hilar-perforant-path-associated …
of granule cell (GC) assemblies during memory acquisition. Hilar-perforant-path-associated …
Somatostatin-expressing interneurons form axonal projections to the contralateral hippocampus
MD Eyre, M Bartos - Frontiers in Neural Circuits, 2019 - frontiersin.org
Conscious memories are critically dependent upon bilateral hippocampal formation, and
interhemispheric commissural projections made by mossy cells and CA3 pyramidal cells …
interhemispheric commissural projections made by mossy cells and CA3 pyramidal cells …
Somatostatin interneurons inhibit excitatory transmission mediated by astrocytic GABAB and presynaptic GABAB and adenosine A1 receptors in the hippocampus
W Shen, Z Li, Y Tang, P Han, F Zhu… - Journal of …, 2022 - Wiley Online Library
GABAergic network activity has been established to be involved in numerous physiological
processes and pathological conditions. Extensive studies have corroborated that GABAergic …
processes and pathological conditions. Extensive studies have corroborated that GABAergic …
Somatostatin and parvalbumin inhibitory synapses onto hippocampal pyramidal neurons are regulated by distinct mechanisms
ME Horn, RA Nicoll - … of the National Academy of Sciences, 2018 - National Acad Sciences
Excitation–inhibition balance is critical for optimal brain function, yet the mechanisms
underlying the tuning of inhibition from different populations of inhibitory neurons are …
underlying the tuning of inhibition from different populations of inhibitory neurons are …