Recent reports support the long-standing hypothesis that acetyl phosphate, a physiologically
relevant small molecule, can serve as a phosphoryl donor to a subset of two-component …

Acetylphosphate: A Novel Link between Lysine Acetylation and Intermediary Metabolism in
Bacteria: Molecular Cell Skip to Main Content Advertisement Molecular Cell This journal offers …

Phosphorylcholine, a crucial component of the pneumococcal cell wall, is essential in
bacterial physiology and in human pathogenesis because it binds to serum components of …

Oxylipins, or oxygenated lipids, are universal signalling molecules across all kingdoms of
life. These molecules, either produced by microbial pathogens or their mammalian host …

Propionate, a major constituent of short chain fatty acids, has recently been reported to be
involved in both prokaryotic and eukaryotic lysine propionylation (Kpr). However, the …

Ornithine lipids (OLs) are phosphorus-free lipids found in many bacteria grown under
phosphate deprivation, a condition that activates the PhoBR system and leads to phosphate …

Phosphorylcholine (ChoP) is a potential candidate for a plurispecific vaccine, because it is
present on surface components of many mucosal organisms, including Haemophilus …

Post-translational modifications (PTMs) have been extensively studied in both eukaryotes
and prokaryotes. Lysine acetylation, originally thought to be a rare occurrence in bacteria, is …

LicA plays a key role in the cell-wall phosphorylcholine biosynthesis of Streptococcus
pneumonia. Here we determined the crystal structures of apo-form LicA at 1.94 Å and two …

Protein acetylation is a universal post-translational modification which is found in both
eukaryotes and prokaryotes. This process is achieved enzymatically by the protein …