Replication of severe acute respiratory syndrome coronavirus 2 in human respiratory epithelium

A Milewska, A Kula-Pacurar, J Wadas, A Suder… - Journal of …, 2020 - Am Soc Microbiol
Currently, there are four seasonal coronaviruses associated with relatively mild respiratory
tract disease in humans. However, there is also a plethora of animal coronaviruses which …

Pathophysiology of infection with SARS‐CoV‐2—What is known and what remains a mystery

S Sridhar, J Nicholls - Respirology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by coronavirus severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused extensive disruption and …

SARS-CoV-2 causes a systemically multiple organs damages and dissemination in hamsters

Z Song, L Bao, P Yu, F Qi, S Gong, J Wang… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread across the
world and impacted global healthcare systems. For clinical patients, COVID-19 not only …

Animal models of COVID-19. I. Comparative virology and disease pathogenesis

CJ Zeiss, S Compton, RT Veenhuis - ILAR journal, 2021 - academic.oup.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has fueled unprecedented
development of animal models to understand disease pathogenesis, test therapeutics, and …

Common laboratory mice are susceptible to infection with the SARS-CoV-2 beta variant

R Kant, L Kareinen, T Smura, TL Freitag, SK Jha… - Viruses, 2021 - mdpi.com
Small animal models are of crucial importance for assessing COVID-19 countermeasures.
Common laboratory mice would be well-suited for this purpose but are not susceptible to …

SARS-CoV-2 infection in the Syrian hamster model causes inflammation as well as type I interferon dysregulation in both respiratory and non-respiratory tissues …

ME Francis, U Goncin, A Kroeker, C Swan… - PLoS …, 2021 - journals.plos.org
COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) infection is a disease affecting several organ systems. A model that …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

A review on SARS-CoV-2 virology, pathophysiology, animal models, and anti-viral interventions

SN Neerukonda, U Katneni - Pathogens, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
CoV disease 2019 (COVID-19) is a highly pathogenic and transmissible CoV that is …

[HTML][HTML] Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling

JS Bednash, VE Kagan, JA Englert, D Farkas… - Translational …, 2022 - Elsevier
The acute respiratory distress syndrome (ARDS) is a common complication of severe COVID-
19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome …

New insights of emerging SARS-CoV-2: epidemiology, etiology, clinical features, clinical treatment, and prevention

G Guo, L Ye, K Pan, Y Chen, D Xing, K Yan… - Frontiers in cell and …, 2020 - frontiersin.org
Since the first reports that the novel coronavirus was showing human-to-human transmission
characteristics and asymptomatic cases, the number of patients with associated pneumonia …