NMR-based structural biology enhanced by dynamic nuclear polarization at high magnetic field

EJ Koers, EAW van Der Cruijsen, M Rosay… - Journal of biomolecular …, 2014 - Springer
Dynamic nuclear polarization (DNP) has become a powerful method to enhance
spectroscopic sensitivity in the context of magnetic resonance imaging and nuclear …

High-temperature dynamic nuclear polarization enhanced magic-angle-spinning NMR

Ü Akbey, AH Linden, H Oschkinat - Applied Magnetic Resonance, 2012 - Springer
Dynamic nuclear polarization (DNP) transfers electron spin-polarization to nuclear spins in
close proximity, increasing sensitivity by two-to-three orders of magnitude. This enables …

[HTML][HTML] Targeted DNP for biomolecular solid-state NMR

D Gauto, O Dakhlaoui, I Marin-Montesinos… - Chemical …, 2021 - pubs.rsc.org
High-field dynamic nuclear polarization is revolutionizing the scope of solid-state NMR with
new applications in surface chemistry, materials science and structural biology. In this …

High-field dynamic nuclear polarization

B Corzilius - Annual review of physical chemistry, 2020 - annualreviews.org
Dynamic nuclear polarization (DNP) is one of the most prominent methods of sensitivity
enhancement in nuclear magnetic resonance (NMR). Even though solid-state DNP under …

Molecular rationale for improved dynamic nuclear polarization of biomembranes

AN Smith, UT Twahir, T Dubroca… - The Journal of …, 2016 - ACS Publications
Dynamic nuclear polarization (DNP) enhanced solid-state NMR can provide orders of
magnitude in signal enhancement. One of the most important aspects of obtaining efficient …

Biomolecular DNP‐Supported NMR Spectroscopy using Site‐Directed Spin Labeling

EAW van Der Cruijsen, EJ Koers… - … A European Journal, 2015 - Wiley Online Library
Dynamic nuclear polarization (DNP) has been shown to greatly enhance spectroscopic
sensitivity, creating novel opportunities for NMR studies on complex and large molecular …

High-field dynamic nuclear polarization for solid and solution biological NMR

AB Barnes, G De Paëpe, PCA Van Der Wel… - Applied magnetic …, 2008 - Springer
Dynamic nuclear polarization (DNP) results in a substantial nuclear polarization
enhancement through a transfer of the magnetization from electrons to nuclei. Recent years …

Dynamic nuclear polarization nuclear magnetic resonance in human cells using fluorescent polarizing agents

BJ Albert, C Gao, EL Sesti, EP Saliba, N Alaniva… - Biochemistry, 2018 - ACS Publications
Solid state nuclear magnetic resonance (NMR) enables atomic-resolution characterization
of the molecular structure and dynamics within complex heterogeneous samples, but it is …

Dynamic nuclear polarization-enhanced NMR on aligned lipid bilayers at ambient temperature

O Jakdetchai, V Denysenkov… - Journal of the …, 2014 - ACS Publications
Dynamic nuclear polarization (DNP)-enhanced solid-state NMR spectroscopy has been
shown to hold great potential for functional studies of membrane proteins at low …

Dynamic nuclear polarization for sensitivity enhancement in biomolecular solid-state NMR

T Biedenbänder, V Aladin, S Saeidpour… - Chemical …, 2022 - ACS Publications
Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …