Current debates in antiphospholipid syndrome: the acquired antibody-mediated thrombophilia

MA Öztürk, IC Haznedaroğlu… - Clinical and applied …, 2004 - journals.sagepub.com
Antiphospholipid (APL) syndrome is the most common form of acquired thrombophilia. It can
cause significant morbidity and even mortality. The term “APL antibodies” represents a …

Incidence, pathophysiology, and clinical manifestations of antiphospholipid syndrome

CO Brock, AS Brohl, SG Običan - Birth Defects Research Part C …, 2015 - Wiley Online Library
Antiphospholipid syndrome (APLS) is a complex systemic disease with a wide variety of
clinical manifestations. In the obstetric population, recurrent early pregnancy loss, fetal loss …

Treatment of thrombotic antiphospholipid syndrome: the rationale of current management—an insight into future approaches

CB Chighizola, T Ubiali… - Journal of Immunology …, 2015 - Wiley Online Library
Vascular thrombosis and pregnancy morbidity represent the clinical manifestations of
antiphospholipid syndrome (APS), which is serologically characterized by the persistent …

Antigen specificity and clinical relevance of antiphospholipid syndrome-related autoantibodies

RR Forastiero, ME Martinuzzo - Current Rheumatology …, 2005 - ingentaconnect.com
The presence of antiphospholipid antibodies (aPL) combined with venous or arterial
thrombosis, and/or obstetric complications defines the antiphospholipid syndrome (APS) …

Obstetrical antiphospholipid syndrome: from the pathogenesis to the clinical and therapeutic implications

T Marchetti, M Cohen… - Journal of Immunology …, 2013 - Wiley Online Library
Antiphospholipid syndrome (APS) is an acquired thrombophilia with clinical manifestations
associated with the presence of antiphospholipid antibodies (aPL) in patient plasma …

Antiphospholipid-mediated thrombosis: interplay between anticardiolipin antibodies and vascular cells

C López-Pedrera, P Buendía… - Clinical and applied …, 2006 - journals.sagepub.com
The antiphospholipid syndrome (APS) is characterized by thrombosis or pregnancy
morbidity in the presence of antiphospholipid autoantibodies (aPL). aPL are a …

Antiphospholipid antibodies: lessons from the bench

T Koike, M Bohgaki, O Amengual, T Atsumi - Journal of autoimmunity, 2007 - Elsevier
Antiphospholipid antibodies (aPL) are an heterogeneous group of circulating
immunoglobulins arising in a wide range of infectious and autoimmune diseases. Since the …

Antiphospholipid syndrome

S Austin, H Cohen - Medicine, 2010 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune disorder in which autoantibody
production can lead to a hypercoagulable state, pregnancy failure and/or a multitude of …

Top 10 clinical research developments in antiphospholipid syndrome

M Barbhaiya, D Erkan - Current rheumatology reports, 2013 - Springer
Persistently positive antiphospholipid antibodies (aPL) with thrombosis and/or pregnancy
morbidity are a characteristic of antiphospholipid syndrome (APS). Although many …

Antiphospholipid syndrome

S Austin, H Cohen - Medicine, 2006 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune disorder in which autoantibody
production may lead to a hypercoagulable state, pregnancy failure and/or a multitude of …