Distinctive features of tumor-infiltrating γδ T lymphocytes in human colorectal cancer
ABSTRACT γδ T cells usually infiltrate many different types of cancer, but it is unclear
whether they inhibit or promote tumor progression. Moreover, properties of tumor-infiltrating …
whether they inhibit or promote tumor progression. Moreover, properties of tumor-infiltrating …
[HTML][HTML] Diversity of tumor-infiltrating, γδ T-cell abundance in solid cancers
G Chabab, F Boissière-Michot, C Mollevi, J Ramos… - Cells, 2020 - mdpi.com
γδ T-cells contribute to the immune response against many tumor types through their direct
cytolytic functions and their capacity to recruit and regulate the biological functions of other …
cytolytic functions and their capacity to recruit and regulate the biological functions of other …
Squamous cell tumors recruit γδ T cells producing either IL17 or IFNγ depending on the tumor stage
E Lo Presti, F Toia, S Oieni, S Buccheri, A Turdo… - Cancer Immunology …, 2017 - AACR
The identification of reciprocal interactions between tumor-infiltrating immune cells and the
microenviroment may help us understand mechanisms of tumor growth inhibition or …
microenviroment may help us understand mechanisms of tumor growth inhibition or …
[HTML][HTML] Pro-tumor γδ T cells in human cancer: polarization, mechanisms of action, and implications for therapy
G Chabab, C Barjon, N Bonnefoy, V Lafont - Frontiers in immunology, 2020 - frontiersin.org
The tumor immune microenvironment contributes to tumor initiation, progression and
response to therapy. Among the immune cell subsets that play a role in the tumor …
response to therapy. Among the immune cell subsets that play a role in the tumor …
[HTML][HTML] Plasticity of γδ T cells: impact on the anti-tumor response
V Lafont, F Sanchez, E Laprevotte… - Frontiers in …, 2014 - frontiersin.org
The tumor immune microenvironment contributes to tumor initiation, progression, and
response to therapy. Among the immune cell subsets that play a role in the tumor …
response to therapy. Among the immune cell subsets that play a role in the tumor …
[HTML][HTML] γδ T cells and tumor microenvironment: from immunosurveillance to tumor evasion
E Lo Presti, G Pizzolato, AM Corsale… - Frontiers in …, 2018 - frontiersin.org
γδ T cells possess cytotoxic antitumor activity mediated by production of proinflammatory
cytokines, direct cytotoxic activity, and regulation of the biological functions of other cell …
cytokines, direct cytotoxic activity, and regulation of the biological functions of other cell …
[HTML][HTML] Tumor-infiltrating γδ T lymphocytes: pathogenic role, clinical significance, and differential programing in the tumor microenvironment
There is increasing clinical evidence indicating that the immune system may either promote
or inhibit tumor progression. Several studies have demonstrated that tumors undergoing …
or inhibit tumor progression. Several studies have demonstrated that tumors undergoing …
Gut γδ T cells as guardians, disruptors, and instigators of cancer
Colorectal cancer is the third most common cancer worldwide with nearly 2 million cases per
year. Immune cells and inflammation are a critical component of colorectal cancer …
year. Immune cells and inflammation are a critical component of colorectal cancer …
γδ T cells in cancer: a small population of lymphocytes with big implications
M Raverdeau, SP Cunningham… - Clinical & …, 2019 - Wiley Online Library
Abstract γδ T cells are a small population of mostly tissue‐resident lymphocytes, with both
innate and adaptive properties. These unique features make them particularly attractive …
innate and adaptive properties. These unique features make them particularly attractive …
[PDF][PDF] Heterogeneity of human γδ T cells and their role in cancer immunity
HW Lee, YS Chung, TJ Kim - Immune Network, 2020 - synapse.koreamed.org
The γδ T cells are unconventional lymphocytes that function in both innate and adaptive
immune responses against various intracellular and infectious stresses. The γδ T cells can …
immune responses against various intracellular and infectious stresses. The γδ T cells can …