Clinical applications of Gallium-68

SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …

Gallium and other main group metal compounds as antitumor agents

MA Jakupec, BK Keppler - Metal ions in biological systems, 2004 - api.taylorfrancis.com
Gallium salts have been explored for their applicability as antineoplastic drugs for more than
two decades, but clinical experience has revealed unfavorable pharmacokinetic and …

The renaissance of the 68Ge/68Ga radionuclide generator initiates new developments in 68Ga radiopharmaceutical chemistry

F Roesch, PJ Riss - Current topics in medicinal chemistry, 2010 - ingentaconnect.com
68Ge/68Ga radionuclide generators have been investigated for almost fifty years now, since
the cyclotronindependent availability of positron emitting 68Ga via the 68Ge/68Ga system …

[PDF][PDF] A gallium-68 radiopharmaceutical that is retained in myocardium: 68Ga [(4, 6-MeO2sal) 2BAPEN]+

BW Tsang, CJ Mathias, MA Green - Journal of Nuclear Medicine, 1993 - Soc Nuclear Med
A solutionof 110mgof Ga (acac) 3 (0.3 mmol) in 10mlof warm ethanol was added to 200 mg
of H3 [(4, 6-MeO2sal) 3BAPEN](0.3 mmol) in 10ml ofwarm ethanol. The mixture was heated …

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

PRWJ Davey, BM Paterson - Molecules, 2022 - mdpi.com
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

Production of gallium-66, a short-lived, positron emitting radionuclide

J Zweit, H Sharma, S Downey - … . Part A. Applied Radiation and Isotopes, 1987 - Elsevier
The excitation functions for the production of 66 Ga and some other radionuclides produced
by the 4 He-particle bombardment of a natural copper target have been measured up to 31 …

The untapped potential of Gallium 68-PET: The next wave of 68Ga-agents

DL Smith, WAP Breeman, J Sims-Mourtada - Applied Radiation and …, 2013 - Elsevier
68Gallium-PET (68Ga-PET) agents have significant clinical promise. The radionuclide can
be produced from a 68Ge/68Ga generator on site and is a convenient alternative to …

Recent advances in chelator design and labelling methodology for 68Ga radiopharmaceuticals

BP Burke, GS Clemente… - Journal of Labelled …, 2014 - Wiley Online Library
Gallium‐68 has the potential to become the technetium‐99m of positron emission
tomography with ideal decay characteristics and a long‐lived parent isotope for generator …

Processing of generator-produced 68Ga for medical application

KP Zhernosekov, DV Filosofov, RP Baum… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The 68Ge/68Ga generator provides an excellent source of positron-emitting 68Ga. However,
newly available “ionic” 68Ge/68Ga radionuclide generators are not necessarily optimized for …

[引用][C] A gallium68 positron cow for medical use

Y Yano, HO Anger - Journal of Nuclear Medicine, 1964 - Soc Nuclear Med
Ga68-EDTA(ethylenediamine tetra-acetic acid). The parent isotope Ge68 de cays with a half
life of 280 days to provide a continuous supply of the daughter isotope Ga 8. The daughter …