Both gut microbiota and cytokines act to atherosclerosis in ApoE−/− mice

Q Liu, Y Li, X Song, J Wang, Z He, J Zhu, H Chen… - Microbial …, 2020 - Elsevier
Background Several studies have suggested a role for the gut microbiome and cytokines in
atherosclerosis development, but combined analyses of the changes of the gut microbiota …

Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis

K Kasahara, T Tanoue, T Yamashita, K Yodoi… - Journal of lipid …, 2017 - ASBMB
The gut microbiota were shown to play critical roles in the development of atherosclerosis,
but the detailed mechanism is limited. The purpose of this study is to clarify the influence of …

A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis

E Brandsma, NJ Kloosterhuis, M Koster… - Circulation …, 2019 - Am Heart Assoc
Rationale: Several studies have suggested a role for the gut microbiota in inflammation and
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …

Bacteroides vulgatus and Bacteroides dorei Reduce Gut Microbial Lipopolysaccharide Production and Inhibit Atherosclerosis

N Yoshida, T Emoto, T Yamashita, H Watanabe… - Circulation, 2018 - Am Heart Assoc
Background: It is increasingly recognized that gut microbiota play a pivotal role in the
development of atherosclerotic cardiovascular disease. Previously, we have reported that …

High fat diet induced atherosclerosis is accompanied with low colonic bacterial diversity and altered abundances that correlates with plaque size, plasma A-FABP and …

YK Chan, MS Brar, PV Kirjavainen, Y Chen, J Peng… - BMC microbiology, 2016 - Springer
Background Atherosclerosis appears to have multifactorial causes–microbial component
like lipopolysaccharides (LPS) and other pathogen associated molecular patterns may be …

Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe−/− Mice

A Lindskog Jonsson, R Caesar, R Akrami… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—To investigate the effect of gut microbiota and diet on atherogenesis. Approach
and Results—Here, we investigated the interaction between the gut microbiota and diet on …

Differential Response of Ileal and Colonic Microbiota in Rats with High-Fat Diet-Induced Atherosclerosis

L Wen, W Xiong, G Wei, L Zhang, Y Liu… - International Journal of …, 2022 - mdpi.com
Growing evidence suggests that gut microbiota are associated with atherosclerosis (AS).
However, the functional heterogeneity of each gut segment gives rise to regional differences …

Circulating gut microbiota-related metabolites influence endothelium plaque lesion formation in ApoE knockout rats

HL Chuang, CC Chiu, C Lo, CC Hsu, JY Liu, SW Hung… - PLos one, 2022 - journals.plos.org
Atherosclerosis is the main cause of cardiac and peripheral vessel infarction in developed
countries. Recent studies have established that gut microbiota and their metabolites play …

The microbiota promotes arterial thrombosis in low-density lipoprotein receptor-deficient mice

K Kiouptsi, S Jäckel, G Pontarollo, A Grill, MJE Kuijpers… - MBio, 2019 - Am Soc Microbiol
Atherosclerotic plaque development depends on chronic inflammation of the arterial wall. A
dysbiotic gut microbiota can cause low-grade inflammation, and microbiota composition was …

[PDF][PDF] An obesogenic diet increases atherosclerosis through promoting microbiota dysbiosis-induced gut lymphocyte trafficking into the periphery

L Laurans, N Mouttoulingam, M Chajadine, A Lavelle… - Cell Reports, 2023 - cell.com
Although high-fat diet (HFD)-induced gut microbiota dysbiosis is known to affect
atherosclerosis, the underlying mechanisms remain to be fully explored. Here, we show that …