COX‐2 and iNOS are critical in advanced glycation end product‐activated chondrocytes in vitro
CY Huang, LF Hung, CCT Liang… - European journal of …, 2009 - Wiley Online Library
Background The advanced glycation end products (AGEs) accumulate in joints of
osteoarthritis patients. This study aimed to investigate the roles of cyclooxygenase‐2 (COX …
osteoarthritis patients. This study aimed to investigate the roles of cyclooxygenase‐2 (COX …
Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes
SS Nah, IY Choi, CK Lee, JS Oh, YG Kim… - …, 2008 - academic.oup.com
Objective. Advanced glycation end products (AGE) accumulate in articular cartilage with
age. We investigated the effects of AGE in primary-cultured human OA chondrocytes …
age. We investigated the effects of AGE in primary-cultured human OA chondrocytes …
[HTML][HTML] Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products …
INTRODUCTION: During aging, advanced glycation end products (AGEs) accumulate in
articular cartilage. In this study we determined whether AGEs induce endoplasmic reticulum …
articular cartilage. In this study we determined whether AGEs induce endoplasmic reticulum …
Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of …
Objective. To investigate whether advanced glycation end products (AGEs) induce the
expression of IL-6 and IL-8 through the receptor for AGEs (RAGE)-activated pathways in …
expression of IL-6 and IL-8 through the receptor for AGEs (RAGE)-activated pathways in …
Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes
FC Liu, LF Hung, WL Wu, DM Chang, CY Huang… - Arthritis research & …, 2010 - Springer
Introduction Accumulation of advanced glycation end products (AGEs) in joints contributes to
the pathogenesis of cartilage damage in osteoarthritis (OA). We aim to explore the potential …
the pathogenesis of cartilage damage in osteoarthritis (OA). We aim to explore the potential …
Advanced glycation end products induce peroxisome proliferator-activated receptor γ down-regulation-related inflammatory signals in human chondrocytes via Toll …
YJ Chen, ML Sheu, KS Tsai, RS Yang, SH Liu - PLoS One, 2013 - journals.plos.org
Accumulation of advanced glycation end products (AGEs) in joints is important in the
development of cartilage destruction and damage in age-related osteoarthritis (OA). The aim …
development of cartilage destruction and damage in age-related osteoarthritis (OA). The aim …
Inflammatory effect of advanced glycation end products on human meniscal cells from osteoarthritic knees
H Hiraiwa, T Sakai, H Mitsuyama, T Hamada… - Inflammation …, 2011 - Springer
Objective To investigate the inflammatory effects of advanced glycation end-products (AGEs)
through the receptor for AGE in meniscal cells from osteoarthritic knees, and examine effects …
through the receptor for AGE in meniscal cells from osteoarthritic knees, and examine effects …
Advanced glycation end‐products induced VEGF production and inflammatory responses in human synoviocytes via RAGE‐NF‐κB pathway activation
YJ Chen, DC Chan, CK Chiang… - Journal of …, 2016 - Wiley Online Library
Aging and diabetes are known to be the major cause to affect the progression of
osteoarthritis (OA). Advanced glycation end products (AGEs) have been observed to …
osteoarthritis (OA). Advanced glycation end products (AGEs) have been observed to …
Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast-like synovial cells
S Franke, M Sommer, C Rüster, T Bondeva… - Arthritis research & …, 2009 - Springer
Introduction Advanced glycation end products (AGEs) have been introduced to be involved
in the pathogenesis of osteoarthritis (OA). The influence of AGEs on osteoarthritic fibroblast …
in the pathogenesis of osteoarthritis (OA). The influence of AGEs on osteoarthritic fibroblast …
Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine …
CY Huang, KY Lai, LF Hung, WL Wu, FC Liu… - Rheumatology, 2011 - academic.oup.com
Objectives. The major risk factor for OA is ageing; however, the mechanisms remain largely
unclear. We investigated the effects and mechanisms of advanced glycation end products …
unclear. We investigated the effects and mechanisms of advanced glycation end products …