Recently, 104 different translocations involving MLL have been described in adult and
pediatric acute leukemia, with more than 64 translocation partner genes now characterized …

Chromosomal rearrangements involving the MLL gene at band 11q23 are the most common
genetic alteration encountered in infant acute myeloid leukemia. Reciprocal translocation …

Dear Editor, Rearrangements involving mixed lineage leukemia (MLL) are common
chromosome aberrations in infant, pediatric and adult acute leukemia, which are generally …

The t (2; 11)(q37; q23) is a rare recurrent cytogenetic abnormality associated with de novo
and therapy-related acute myeloid leukemia, resulting in a MLL-SEPT2 fusion gene. We …

We present the characterization at the RNA level of an acute myeloid leukemia with at (11;
17)(q23; q25) and a MLL rearrangement demonstrated by FISH. Molecular analysis led to …

We have identified a new mixed lineage leukemia (MLL) gene fusion partner in a patient
with treatment-related acute myeloid leukemia (AML) presenting at (2; 11)(q37; q23) as the …

Abstract t (X; 11)(q24; q23) is a recurring chromosomal translocation in pediatric acute
myeloid leukemia. The rearrangement results in fusion of MLL at 11q23 with SEPT6 at Xq24 …

As a result of recurrent chromosomal translocations in acute leukemias, the mixed-lineage-
leukemia (MLL) gene fuses with a variety of partner genes, which include several members …

We report a case of acute myeloid leukemia (AML) with two unrelated clones, one of which
was t (11; 17)(q23; q25) carrying MLL-SEPT9 fusion transcripts. The patient was a 71-year …

Chromosomal rearrangements affecting the MLL gene are associated with high-risk
pediatric, adult and therapy-associated acute leukemia. In this study, conventional …