Cytotoxic effects of zearalenone and its metabolites and antioxidant cell defense in CHO-K1 cells

E Tatay, G Font, MJ Ruiz - Food and Chemical Toxicology, 2016 - Elsevier
Zearalenone (ZEA) and its metabolites (α-zearalenol; α-ZOL, β-zearalenol; β-ZOL) are
secondary metabolites of Fusarium fungi that produce cell injury. The present study explores …

Oxidative damage and disturbance of antioxidant capacity by zearalenone and its metabolites in human cells

E Tatay, S Espin, AJ Garcia-Fernandez, MJ Ruiz - Toxicology in Vitro, 2017 - Elsevier
Mycotoxin contamination of foods and feeds represent a serious problem worldwide.
Zearalenone (ZEA) is a secondary metabolite produced by Fusarium species. This study …

Zearalenone induces oxidative damage involving Keap1/Nrf2/HO-1 pathway in hepatic L02 cells

K Wu, X Liu, M Fang, Y Wu, Z Gong - Molecular & Cellular Toxicology, 2014 - Springer
Zearalenone (ZEA), a mycotoxin produced by Fusarium fungi, is found in cereal crops.
Although the toxic effects of ZEA have been well characterized, the mechanism is not clear …

Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites

DE Marin, GC Pistol, CV Bulgaru, I Taranu - … -Schmiedeberg's archives of …, 2019 - Springer
Zearalenone (ZEA), a mycotoxin produced by several Fusarium spp., is most commonly
found as a contaminant in stored grain. ZEA derivatives (α-zearalenol (α-ZOL), β-zearalenol …

Zearalenone induced toxicity in SHSY-5Y cells: the role of oxidative stress evidenced by N-acetyl cysteine

M Venkataramana, SC Nayaka, T Anand… - Food and chemical …, 2014 - Elsevier
Zearalenone (ZEN) is a mycotoxin from Fusarium species commonly found in many food
commodities and are known to cause reproductive disorders, genotoxic and …

Oxidative stress, glutathione, and gene expression as key indicators in SH-SY5Y cells exposed to zearalenone metabolites and beauvericin

F Agahi, N Alvarez-Ortega, G Font, A Juan-Garcia… - Toxicology Letters, 2020 - Elsevier
The co-presence of mycotoxins from fungi of the genus Fusarium is a common fact in raw
food and food products, as trace levels of them or their metabolites can be detected, unless …

Protective effect of aqueous extract of Allium sativum against zearalenone toxicity mediated by oxidative stress

S Abid-Essefi, C Zaied, C Bouaziz, IB Salem… - Experimental and …, 2012 - Elsevier
Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin produced by several species of
Fusarium in cereals and agricultural products. It has been implicated in several …

[HTML][HTML] Study of enzymatic activity in human neuroblastoma cells SH-SY5Y exposed to zearalenone's derivates and beauvericin

F Agahi, A Juan-García, G Font, C Juan - Food and Chemical Toxicology, 2021 - Elsevier
Abstract Beauvericin (BEA), α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL), are produced
by several Fusarium species that contaminate cereal grains. These mycotoxins can cause …

Cytotoxicity effects induced by Zearalenone metabolites, α Zearalenol and β Zearalenol, on cultured Vero cells

ZOB Othmen, E El Golli, S Abid-Essefi, H Bacha - Toxicology, 2008 - Elsevier
Zearalenone (Zen) is a non-steroidal estrogenic mycotoxin produced by several species of
Fusarium. It has been implicated in several mycotoxicosis in farm animals and in humans …

Toxicity of zearalenone and its nutritional intervention by natural products

S Jing, C Liu, J Zheng, Z Dong, N Guo - Food & Function, 2022 - pubs.rsc.org
Zearalenone (ZEN) is a toxic secondary metabolite mainly produced by fungi of the genus
Fusarium, and is often present in various food and feed ingredients such as corn and wheat …