Unsuspected Bronchospasm in Association with Topical Timolola Common Problem in Elderly People: Can We easily identify Those affected and do Cardioselective …

P Diggory, P Heyworth, G Chau, S McKENZIE… - Age and …, 1994 - academic.oup.com
The extent of impairment of respiratory function in a group of 52 elderly, glaucomatous
patients receiving topical timolol therapy was investigated. To predict those patients who …

Avoiding unsuspected respiratory side-effects of topical timolol with cardioselective or sympathomimetic agents

P Diggory, A Cassels-Brown, JS Hillman, LM Abbey - The Lancet, 1995 - thelancet.com
Topical timolol given for the treatment or chronic simple glaucoma may cause unrecognised
bronchospasm among elderly people. We recruited 80 patients aged over 60 years, who …

Topical beta-blockade with intrinsic sympathomimetic activity offers no advantage for the respiratory and cardiovascular function of elderly people

P Diggory, A Cassels-Brown, C Fernandez - Age and ageing, 1996 - academic.oup.com
Topical therapy with beta-antagonists, such as timolol, may cause unrecognized impairment
of respiratory and cardiovascular function in elderly people. Beta-antagonists with intrinsic …

Improved lung function tests on changing from topical timolol: non-selective beta-blockade impairs lung function tests in elderly patients

P Diggory, P Heyworth, G Chau, S McKenzie… - Eye, 1993 - nature.com
Fifty-two elderly glaucomatous patients, without a history of asthma or obstructive airways
disease, who were using topical timolol for control of intraocular pressure were recruited …

The effect of topical ophthalmic instillation of timolol and betaxolol on lung function in asthmatic subjects

TL Dunn, MJ Gerber, AS Shen… - American Review of …, 1986 - atsjournals.org
The propensity of systemic beta-adrenergic blockers to cause bronchoconstriction in
patients with reactive airway disease is well recognized. A study was carried out to …

The effect of timolol drops on respiratory function

SA Sadiq, K Fielding, SA Vernon - Eye, 1998 - nature.com
Purpose Recently, attention has been focused on the adverse drug reactions of topical
timolol, especially with regard to respiratory function in the elderly. This study was designed …

Temporal variation in the effects of ophthalmic timolol on cardiovascular and respiratory functions in healthy men

MH Umetsuki, T Kotegawa, K Nakamura… - The Journal of …, 1997 - Wiley Online Library
This study examined the effects of ophthalmic timolol and time of administration on
cardiovascular and respiratory functions in healthy young male volunteers. Eight participants …

Changes in lung function following administration of eyedrops containing timolol, metipranolol, pindolol and pilocarpine in healthy probands and patients with mild …

E Böhm, H Fabel - Klinische Wochenschrift, 1987 - europepmc.org
Lung function was studied double blind and randomized in 5 patients with mild asthma
bronchiale and 10 normal adults before and 30, 60 and 90 minutes after one drop of 0.5 …

Randomised, controlled trial of spirometric changes in elderly people receiving timolol or betaxolol as initial treatment for glaucoma

P Diggory, A Cassels-Brown, A Vail… - British journal of …, 1998 - bjo.bmj.com
AIM To investigate respiratory and cardiovascular side effects in elderly people in the first 12
months after commencing topical β antagonists. METHODS 40 patients (mean age 74 years) …

Pulmonary effects of topical timolol

NB Charan, S Lakshminarayan - Archives of Internal Medicine, 1980 - jamanetwork.com
Timolol, a β-adrenergic blocking agent, recently became available for the treatment of
glaucoma. We report the occurrence of acute bronchospasm in a previously asymptomatic …