Benefit and application of antibodies against the H1 carbohydrate recognition domain of the human hepatic asialoglycoprotein receptor
R Born - 2005 - edoc.unibas.ch
The asialoglycoprotein receptor (ASGPR), composed of the subunits H1 and H2, is
predominantly expressed on the sinusoidal surface of mammalian hepatocytes and involved …
predominantly expressed on the sinusoidal surface of mammalian hepatocytes and involved …
[PDF][PDF] Targeting hepatocytes via the asialoglycoprotein-receptor
D Stokmaier - 2010 - edoc.unibas.ch
The asialoglycoprotein-receptor (ASGP-R) is a C-type lectin predominantly expressed on
the sinusoidal surface of mammalian hepatocytes and is responsible for the blood-clearance …
the sinusoidal surface of mammalian hepatocytes and is responsible for the blood-clearance …
Physiological roles of asialoglycoprotein receptors (ASGPRs) variants and recent advances in hepatic-targeted delivery of therapeutic molecules via ASGPRs
J Hu, J Liu, D Yang, M Lu, J Yin - Protein and peptide letters, 2014 - ingentaconnect.com
The asialoglycoprotein receptor (ASGPR) is a high-capacity C-type lectin receptor mainly
expressed on mammalian hepatic cells. The physiological function of ASGPR has not been …
expressed on mammalian hepatic cells. The physiological function of ASGPR has not been …
[PDF][PDF] Design and synthesis of high affinity ligands for the asialoglycoprotein receptor (ASGP-R)
O Khorev - 2007 - edoc.unibas.ch
The asialoglycoprotein receptor (ASGP-R) is a carbohydrate-binding protein from the C-type
lectin family that is expressed exclusively and in high numbers on mammalian hepatocytes …
lectin family that is expressed exclusively and in high numbers on mammalian hepatocytes …
Linking structure and function of the asialoglycoprotein receptor H1-CRD using site-directed mutagenesis and isotope labeling
AK Johansson - 2007 - edoc.unibas.ch
The asialoglycoprotein receptor (ASGP-R) is a C-type lectin, abundantly expressed on
hepatocytes. It mediates the clearance of desialylated glycoproteins carrying terminal …
hepatocytes. It mediates the clearance of desialylated glycoproteins carrying terminal …
A monoclonal antibody to rat asialoglycoprotein receptor that recognizes an epitope specific to its major subunit
M Shimada, M Mizuno, T Uesu, J Nasu, H Okada… - Hepatology …, 2003 - Elsevier
We previously developed three mouse monoclonal antibodies (MoAbs) identifying the
domain-specific plasma membrane proteins of rat hepatocytes. Based on the results of …
domain-specific plasma membrane proteins of rat hepatocytes. Based on the results of …
High-yield purification and characterization of human asialoglycoprotein receptor
U Treichel, T Schreiter, KHM Zumbuschenfelde… - Protein Expression and …, 1995 - Elsevier
The human asialoglycoprotein receptor (ASGPR) represents a major component of the
hepatocellular membrane. To study its native composition, approximately 30% of receptor …
hepatocellular membrane. To study its native composition, approximately 30% of receptor …
Production and characterization of specific asialoglycoprotein receptor antibodies
Y Kohgo, J KATO, R NAKAYA, Y MOGI, H YAGO… - Hybridoma, 1993 - liebertpub.com
Monoclonal antibodies (MoAbs) were produced by immunizing BALB/c mice with
asialoglycoprotein receptor (AGPR) purified from human liver. The purity of AGPR was …
asialoglycoprotein receptor (AGPR) purified from human liver. The purity of AGPR was …
Detection of the asialoglycoprotein receptor on cell lines of extrahepatic origin
JH Park, EW Cho, SY Shin, YJ Lee, KL Kim - Biochemical and Biophysical …, 1998 - Elsevier
The asialoglycoprotein receptor (ASGPR) is the first lectin discovered in mammals. Despite
its significant biological role in binding and internalization of desialyated glycoproteins, at …
its significant biological role in binding and internalization of desialyated glycoproteins, at …
The major subunit of the asialoglycoprotein receptor is expressed on the hepatocellular surface in mice lacking the minor receptor subunit
JR Braun, TE Willnow, S Ishibashi, G Ashwell… - Journal of Biological …, 1996 - ASBMB
The mammalian asialoglycoprotein receptor (ASGPR) is located on the sinusoidal
membrane of hepatocytes where it binds and endocytoses galactose-terminated …
membrane of hepatocytes where it binds and endocytoses galactose-terminated …